R Mentlein
Overview
Explore the profile of R Mentlein including associated specialties, affiliations and a list of published articles.
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102
Citations
1824
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Recent Articles
1.
Akay I, Oxmann D, Helfenstein A, Mentlein R, Schunke M, Hassenpflug J, et al.
Osteoarthritis Cartilage
. 2009 Dec;
18(3):389-96.
PMID: 19944200
Objective: Implantation of autologous chondrocytes (AC) is a promising option for the treatment of cartilage defects, but problems with cell harvesting, dedifferentiation, or the donor age limit the clinical outcome....
2.
Varoga D, Tohidnezhad M, Paulsen F, Wruck C, Brandenburg L, Mentlein R, et al.
J Anat
. 2008 Dec;
213(6):749-57.
PMID: 19094191
Osteomyelitis often causes functional impairment due to tissue destruction. This report demonstrates a novel previously unappreciated role of osteoblasts. Samples of osteomyelitic bone and bacterially challenged osteoblasts produce increased amounts...
3.
Varoga D, Wruck C, Tohidnezhad M, Brandenburg L, Paulsen F, Mentlein R, et al.
Histochem Cell Biol
. 2008 Oct;
131(2):207-18.
PMID: 18925411
Gram-positive bacterial bone infections are an important cause of morbidity particularly in immunocompromised patients. Antimicrobial peptides (AP) are effectors of the innate immune system and directly kill microorganisms in the...
4.
Oxmann D, Held-Feindt J, Stark A, Hattermann K, Yoneda T, Mentlein R
Oncogene
. 2008 Jan;
27(25):3567-75.
PMID: 18223685
Endoglin is a cell-surface adhesion protein as well as a coreceptor for transforming growth factor-beta (TGF-beta). It is located on endothelial and few other cells, but also found on certain...
5.
Varoga D, Paulsen F, Mentlein R, Fay J, Kurz B, Schutz R, et al.
J Pathol
. 2006 Sep;
210(3):315-24.
PMID: 16981238
Bacterial arthritis is a progressive joint disease which includes rapid destruction of articular cartilage even after clearance of the causal factor. The resulting post-infectious arthropathy is mainly characterized by self-perpetuating...
6.
Pufe T, Groth G, Goldring M, Tillmann B, Mentlein R
Osteoarthritis Cartilage
. 2006 Sep;
15(2):155-62.
PMID: 16949312
Objective: Pleiotrophin (PTN) is a secreted heparin-binding peptide expressed in mesodermal and neuroectodermal cells during development, but rarely in adult tissues. In fetal and juvenile, but not in mature cartilage,...
7.
Varoga D, Paulsen F, Kohrs S, Grohmann S, Lippross S, Mentlein R, et al.
J Pathol
. 2006 Apr;
209(2):166-73.
PMID: 16622898
Defensins are antibiotic peptides that are involved in host defence at epithelial and mesenchymal surfaces. Previous studies have shown the induction of human beta-defensin-3 (HBD-3) in osteoarthritic joints, suggesting that...
8.
Pufe T, Petersen W, Mentlein R, Tillmann B
Scand J Med Sci Sports
. 2005 Jul;
15(4):211-22.
PMID: 15998338
More than 100 years ago Wilhelm Roux (1895) introduced the term "functional adaptation to anatomy and physiology". Compared with other organ systems the functional adaptation processes are best identifiable in...
9.
Mest H, Mentlein R
Diabetologia
. 2005 Mar;
48(4):616-20.
PMID: 15770466
Inhibitors of the regulatory protease dipeptidyl peptidase-IV (DPP-IV) are currently under development in preclinical and clinical studies (several pharmaceutical companies, now in Phase III) as potential drugs for the treatment...
10.
Becker R, Pufe T, Kulow S, Giessmann N, Neumann W, Mentlein R, et al.
J Bone Joint Surg Br
. 2004 Sep;
86(7):1082-7.
PMID: 15446544
Our aim was to investigate vascular endothelial growth factor (VEGF) expression after lacerations of a meniscus in a rabbit model. Specimens of meniscus were examined using immunohistochemistry, enzyme-linked immunoassay and...