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R M OHara Jr

Explore the profile of R M OHara Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 346
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Recent Articles
1.
Zhang T, Fresnay S, Welty E, Sangrampurkar N, Rybak E, Zhou H, et al.
Am J Transplant . 2011 Jul; 11(8):1599-609. PMID: 21749640
Selective blockade of CD28 is a promising therapy to inhibit pathogenic alloimmunity. However, evaluation of this approach in transplantation has been very limited. Using a novel nonactivating single-chain Fv-based reagent...
2.
Donaldson D, Whitters M, Fitz L, Neben T, Finnerty H, Henderson S, et al.
J Immunol . 1998 Sep; 161(5):2317-24. PMID: 9725226
Two components of a receptor complex for IL-13, the IL-4R and a low affinity IL-13-binding chain, IL-13R alpha 1, have been cloned in mice and humans. An additional high affinity...
3.
Rothe H, OHara Jr R, Martin S, Kolb H
Diabetologia . 1997 Jun; 40(6):641-6. PMID: 9222642
The macrophage product interleukin (IL)-12 is known to drive Th1 reactions in physiological and pathological immune responses. Here we report that treatment with the homodimeric IL-12p40 subunit, an antagonist of...
4.
OHara Jr R, Henderson S, Nagelin A
Ann N Y Acad Sci . 1996 Oct; 795:241-9. PMID: 8958935
The effects of interleukin-12 on autoimmune diabetes in nonobese diabetic mice was examined. IL-12 was given, intraperitoneally, to NOD females in two different treatment protocols: three times a week, for...
5.
OHara Jr R, Byrne M, Kuchroo V, Nagelin A, Whitters M, Jayaraman S, et al.
J Immunol . 1995 Mar; 154(5):2075-81. PMID: 7868884
Previous studies utilizing NP (4-hydroxy, 3-nitrophenyl acetyl hapten)-specific, T suppressor hybridomas have indicated that expression of TCR-alpha, but not TCR-beta, mRNA is required for expression of Ag-specific suppressor factor bioactivity....
6.
OHara Jr R
Immunol Res . 1995 Jan; 14(4):252-62. PMID: 8722042
Few areas of immunologic research have endured such strident criticism or engendered such fainthearted support as the study of antigen-specific suppression of the immune response. Although enjoying a modest resurgence...
7.
Byrne M, OHara Jr R, Kuchroo V, Jayaraman S, Rao A, Dorf M, et al.
Ann N Y Acad Sci . 1993 Jun; 685:611-3. PMID: 8363270
No abstract available.
8.
Kuchroo V, Byrne M, Atsumi Y, Greenfield E, Connolly J, Whitters M, et al.
Proc Natl Acad Sci U S A . 1991 Oct; 88(19):8700-4. PMID: 1833764
Antigen-specific suppressor T-cell hybridomas release soluble suppressor factors (TsF) in the supernatant that modulate both in vivo delayed-type hypersensitivity and in vitro plaque-forming cell responses in an antigen-specific manner. To...
9.
Collins M, Kuchroo V, Whitters M, OHara Jr R, Kelleher K, Kubo R, et al.
J Immunol . 1990 Nov; 145(9):2809-19. PMID: 2170525
We have examined the expression of TCR genes in 4-hydroxy-3-nitrophenyl-acetyl (NP)-specific Ts cell hybridomas. Each of three independently isolated hybridomas expressed in-frame TCR alpha-chain rearrangements derived from the original suppressor...
10.
Wood C, Dorner A, Morris G, Alderman E, Wilson D, OHara Jr R, et al.
J Immunol . 1990 Nov; 145(9):3011-6. PMID: 2120343
The expression of lambda L and microH chain cDNA was examined in Chinese hamster ovary cells. Each cDNA was linked to a different, amplifiable, selectable drug marker gene, and expression...