R L Spencer
Overview
Explore the profile of R L Spencer including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
2210
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Recent Articles
1.
Pace T, Cole M, Ward G, Kalman B, Spencer R
Stress
. 2012 Mar;
4(4):319-31.
PMID: 22432149
The present study sought to identify dishabituation of the hypothalamic-pituitary-adrenal(HPA) axis response to different psychological stressors. Young adult male Sprague Dawley rats were exposed to five, 1 h sessions of...
2.
Newsom R, Osterlund C, Masini C, Day H, Spencer R, Campeau S
Neuroscience
. 2011 Dec;
204:64-73.
PMID: 22138156
Altered regulation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with stress-induced changes in cognitive, emotional, and physical health. Recent evidence indicates that the endogenous cannabinoid (eCB) system may modulate HPA-axis...
3.
Osterlund C, Jarvis E, Chadayammuri A, Unnithan R, Weiser M, Spencer R
J Neuroendocrinol
. 2011 Sep;
23(12):1241-51.
PMID: 21929693
The negative-feedback actions of corticosterone (CORT) depend on both phasic and tonic CORT secretion patterns to regulate hypothalamic-pituitary-adrenal (HPA) axis activity. How these two different CORT secretion pattens influence specific...
4.
Weiser M, Osterlund C, Spencer R
J Neuroendocrinol
. 2011 Sep;
23(12):1231-40.
PMID: 21910768
Endogenous glucocorticoid negative-feedback influence on the hypothalamic-pituitary-adrenal (HPA) axis depends on glucocorticoid actions exerted on multiple glucocorticoid-sensitive tissues and differential glucocorticoid effects that are expressed within several distinct temporal domains....
5.
Peterson B, Ivanova E, Spencer R, Hart G, Lin J, Stark T, et al.
J Xray Sci Technol
. 2011 Feb;
5(1):43-51.
PMID: 21307476
This paper describes a combined theoretical and experimental approach to understanding the capillary spark discharge with specific application to use as a soft x-ray or extreme ultraviolet laser source. Atomic...
6.
Weinberg M, Grissom N, Paul E, Bhatnagar S, Maier S, Spencer R
Neuroscience
. 2010 Jul;
170(1):138-48.
PMID: 20600641
Control over an aversive experience can greatly impact the organism's response to subsequent stressors. We compared the effects of escapable (ES) and yoked inescapable (IS) electric tail shocks on the...
7.
Weinberg M, Johnson D, Bhatt A, Spencer R
Neuroscience
. 2010 Apr;
168(3):744-56.
PMID: 20394807
Recent findings suggest that the expression of hypothalamic-pituitary-adrenal (HPA) axis stress response adaptation in rats depends on top-down neural control. We therefore examined whether the medial prefrontal cortex (mPFC) modulates...
8.
Chao H, Spencer R, Sakai R, McEwen B
Mol Cell Neurosci
. 2009 Nov;
3(6):529-35.
PMID: 19912896
GAP-43 is expressed in axonal growth cones during development and regeneration. High levels of GAP-43 persist in the adult hippocampus, reflecting perhaps the ongoing neurogenesis and synaptic plasticity characteristic of...
9.
Weinberg M, Girotti M, Spencer R
Neuroscience
. 2007 Oct;
150(2):478-86.
PMID: 17936518
The protein product of the fra-2 gene (Fra-2), a fos-family member, can compete with Fos protein for participation in activating protein-1 (AP-1) transcription factor complexes and each protein can contribute...
10.
Francis A, Pace T, Ginsberg A, RUBIN B, Spencer R
Neuroscience
. 2006 Jun;
141(3):1503-15.
PMID: 16806720
The experiments described herein present a method for tracking diffusion of the glucocorticoid receptor agonist RU28362 in brain following i.c.v. drug administration. A useful property of glucocorticoid receptor is that...