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R L Bronaugh

Explore the profile of R L Bronaugh including associated specialties, affiliations and a list of published articles. Areas
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Articles 49
Citations 375
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Recent Articles
1.
Eppler A, Kraeling M, Wickett R, Bronaugh R
Food Chem Toxicol . 2007 Jul; 45(11):2109-17. PMID: 17602815
Arachidonic acid (AA), a precursor of pro-inflammatory mediators, and its glycerin ester, glyceryl arachidonate (GA), are reportedly used in cosmetic products. In vitro skin penetration of AA and GA and...
2.
Kraeling M, Yourick J, Bronaugh R
Food Chem Toxicol . 2004 Aug; 42(10):1553-61. PMID: 15304302
Concerns about the safety of diethanolamine (DEA) have been raised by the National Toxicology Program (NTP). Therefore, we measured the extent of DEA absorption in human skin relevant to exposures...
3.
Jung C, Wickett R, Desai P, Bronaugh R
Food Chem Toxicol . 2003 May; 41(6):885-95. PMID: 12738194
The Cosmetic Ingredient Review Expert Panel found insufficient data to conclude that catechol could be used safely in permanent hair dye products. Information was lacking on the extent of oxidation...
4.
Bronaugh R
Ann N Y Acad Sci . 2000 Nov; 919:188-91. PMID: 11083108
In vitro skin absorption studies are commonly used to estimate in vivo skin absorption in topical safety and efficacy evaluations. In vitro studies are more economical and result in minimization...
5.
Yourick J, Bronaugh R
Toxicol Appl Pharmacol . 2000 Jun; 166(1):13-23. PMID: 10873714
2-Nitro-p-phenylenediamine (2NPPD) is a dye used in semipermanent and permanent (tinting color) hair dye formulations. National Toxicology Program toxicology and carcinogenesis testing of 2NPPD has raised concerns about its safety....
6.
Hood H, Kraeling M, Robl M, Bronaugh R
Food Chem Toxicol . 1999 Nov; 37(11):1105-11. PMID: 10566882
The barrier integrity of hairless guinea pig skin after treatment with an alpha hydroxy acid was assessed through in vivo topical application of an oil-in-water emulsion containing 5 or 10%...
7.
Kraeling M, Reddy G, Bronaugh R
J Appl Toxicol . 1998 Dec; 18(6):387-92. PMID: 9840746
The percutaneous absorption of 1,3,5-trinitrobenzene (TNB) was studied in viable skin from hairless guinea pigs (HGP), Fischer 344 rats and humans. Skin was dermatomed and assembled in flow-through diffusion cells...
8.
Yourick J, Bronaugh R
J Appl Toxicol . 1997 May; 17(3):153-8. PMID: 9250536
Coumarin is widely used as a fragrance in cosmetics, perfumes and soaps. The food and Drug Administration banned coumarin use in food because of reports that coumarin produced hepatotoxicity in...
9.
MacPherson S, Barton C, Bronaugh R
Toxicol Appl Pharmacol . 1996 Oct; 140(2):436-43. PMID: 8887461
A physiologically based pharmacokinetic (PB PK) model was developed to predict plasma levels of benzoic acid (BA) in the hairless guinea pig after topical exposure at three finite dose levels....
10.
Hood H, Wickett R, Bronaugh R
Food Chem Toxicol . 1996 May; 34(5):483-8. PMID: 8655098
The percutaneous absorption of the fragrance fixative musk xylol was measured in vitro in human and hairless guinea pig skin. For comparison, musk xylol was applied to skin in an...