R K Iles
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Explore the profile of R K Iles including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
358
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Recent Articles
1.
Iles R, Delves P, Butler S
Mol Cell Endocrinol
. 2010 Jul;
329(1-2):62-70.
PMID: 20654692
The role that hCG might play in the oncogenic process in cancer is certainly complex. We know that the expression of hCG and its beta subunit is a widespread phenomenon...
2.
Wen X, Perrett D, Patel P, Li N, Docherty S, Tozer A, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2009 Nov;
877(31):3946-52.
PMID: 19889587
Some of the major serum proteins that are also found in follicular fluid, including transferrin, alpha-macroglobulin and albumin, are thought to play a role in oocyte maturation. This study set...
3.
Li D, Wen X, Ghali L, Al-Shalabi F, Docherty S, Purkis P, et al.
Histopathology
. 2008 Aug;
53(2):147-55.
PMID: 18752498
Aims: To investigate the correlation of beta-subunit of human chorionic gonadotrophin (hCG beta) expression by cervical carcinomas with measures of tumour apoptosis. Methods And Results: Eighty-nine cervical carcinoma patients' samples...
4.
Iles R
Mol Cell Endocrinol
. 2006 Oct;
260-262:264-70.
PMID: 17069968
Ectopic expression of the beta-subunit of human chorionic gonadotropin (hCG) is now a recognized phenomenon in 20-40% of all common epithelial carcinoma arising from mucosal epithelia such as bladder, cervix,...
5.
Delves P, Iles R, Roitt I, Lund T
Mol Cell Endocrinol
. 2006 Oct;
260-262:276-81.
PMID: 17049720
The heterodimeric 'pregnancy-specific' hormone human chorionic gonadotropin (hCG) has been used as the basis for a contraceptive vaccine. More recently, the observation that hCG, particularly in the form of the...
6.
Otite U, Baithun S, Chinegwundoh F, Nargund V, Iles R
Tumour Biol
. 2006 May;
27(4):181-6.
PMID: 16651852
The aim of this study was to prospectively evaluate the potential role of elevated urinary/serum human chorionic gonadotrophin-beta (hCGbeta) in prostate cancer prognosis. 104 patients with newly diagnosed prostate cancers...
7.
Thurairaja R, Iles R, Jefferson K, McFarlane J, Persad R
Urol Int
. 2006 Jan;
76(1):67-71.
PMID: 16401924
Introduction: To determine if amino-terminal propeptide of type 1 procollagen (P1NP) is reliable as a predictor of prostate cancer bone metastases and assess its value as a prognostic indicator of...
8.
Tozer A, Iles R, Iammarrone E, Nica R, Gillott C, Xusong W, et al.
Hum Reprod
. 2004 Oct;
19(11):2561-8.
PMID: 15471924
Background: The aim of this study was to evaluate the functional characteristics of granulosa cell populations of individual follicles of women undergoing controlled ovarian stimulation (COS) for IVF/ICSI in whom...
9.
Tozer A, Iles R, Iammarrone E, Gillott C, Al-Shawaf T, Grudzinskas J
Hum Reprod
. 2004 Mar;
19(3):522-8.
PMID: 14998945
Background: The aim of this study was to assess the effect of withholding gonadotrophins (coasting) during controlled ovarian stimulation (COS) on individual follicle concentrations of follicular fluid vascular endothelial growth...
10.
Jacoby E, Kicman A, Iles R
J Mol Endocrinol
. 2003 Apr;
30(2):239-52.
PMID: 12683946
Metabolism of the human chorionic gonadotrophin (hCG)- and LHbeta-subunits (hCGbeta, LHbeta) terminates with the urinary excretion of core fragment (hCGbetacf, LHbetacf) molecules that retain antigenic shape and constituent N-linked carbohydrate...