R J Shebuski
Overview
Explore the profile of R J Shebuski including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
366
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Recent Articles
1.
Porcari A, Shebuski R
J Pharmacol Exp Ther
. 2000 Nov;
295(3):1291-5.
PMID: 11082467
No abstract available.
2.
Kumar A, Hoover J, Simmons C, Lindner V, Shebuski R
Circulation
. 1998 Jan;
96(12):4333-42.
PMID: 9416901
Background: Inflammatory reactions such as leukocyte activation with platelet adherence and release of inflammatory mediators occur after percutaneous transluminal coronary angioplasty and may play a role in restenosis. Vascular remodeling...
3.
Mills C, Northrup J, Hullinger T, Simmons C, Shebuski R, Jones D
Cardiovasc Res
. 1996 Nov;
32(5):954-61.
PMID: 8944827
Objective: Restenosis is a common problem which limits the effectiveness of percutaneous transluminal coronary angioplasty (PTCA). The cellular mechanisms of restenosis appear to involve smooth muscle cell (SMC) migration to...
4.
Leadley Jr R, Humphrey W, Erickson L, Shebuski R
Thromb Haemost
. 1995 Dec;
74(6):1583-90.
PMID: 8772241
The effect of endothelin-1 (ET-1) on thrombus formation in vivo was evaluated in two well-established canine models of coronary artery thrombosis. First, the possible antithrombotic effect of ET-1 was examined...
5.
Toombs C, DeGraaf G, Martin J, Geng J, Anderson D, Shebuski R
J Pharmacol Exp Ther
. 1995 Nov;
275(2):941-9.
PMID: 7473186
It has been established that the fibrin content of a developing thrombus can be dramatically reduced with the use of the GA6 monoclonal antibody, which is directed against P-selectin (CD62p)....
6.
Hartman J, Anderson D, Wiltse A, Lane C, Rosenbloom C, Manning A, et al.
Cardiovasc Res
. 1995 Jul;
30(1):47-54.
PMID: 7553723
Objective: A blocking monoclonal antibody to intercellular adhesion molecule-1 (ICAM-1), CL18/6, previously has been demonstrated to inhibit neutrophil attachment to isolated vascular endothelium and cardiomyocytes. Due to the well known...
7.
Virkhaus R, Lucchesi B, Simpson P, Shebuski R
J Pharmacol Exp Ther
. 1995 May;
273(2):569-75.
PMID: 7752057
No abstract available.
8.
Manning A, Bell F, Rosenbloom C, Chosay J, Simmons C, Northrup J, et al.
J Inflamm
. 1995 Jan;
45(4):283-96.
PMID: 8867672
Leukocytes accumulate at sites of inflammation in response to the induced expression of endothelial cell adhesion molecules. The nuclear transcription factor kappa B (NF-kappa B) plays a critical role in...
9.
Hartman J, Kurc G, Hullinger T, Wall T, Sheehy R, Shebuski R
J Pharmacol Exp Ther
. 1994 Sep;
270(3):1071-6.
PMID: 7523655
The objective of this investigation was to determine the role of nitric oxide synthase in the action of the angiotensin-converting enzyme inhibitor, ramiprilat, to reduce myocardial ischemia/reperfusion injury. Ramiprilat, the...
10.
Toombs C, Moore T, Shebuski R
Pharmacology
. 1994 Aug;
49(2):96-104.
PMID: 7972326
We have previously reported that cromakalim and U-89232 reduce infarct size in a rabbit model of myocardial ischemia. Because U-89232 appeared to lack activity in the vasculature, we tested its...