R Imrich
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Explore the profile of R Imrich including associated specialties, affiliations and a list of published articles.
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40
Citations
238
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Recent Articles
1.
Ranganath L, Khedr M, Milan A, Davison A, Hughes A, Norman B, et al.
Nutrients
. 2024 Aug;
16(16).
PMID: 39203858
Introduction: Protein nutrition disorder in alkaptonuria (AKU), resulting in increased homogentisic acid (HGA) before nitisinone therapy and increased tyrosine (TYR) during nitisinone therapy, may benefit from dietetic intervention. The aim...
2.
Ranganath L, Khedr M, Norman B, Hughes J, Imrich R, Arnoux J, et al.
Mol Genet Metab Rep
. 2024 Jun;
40:101097.
PMID: 38846518
Background: Increased homogentisic acid (HGA) in alkaptonuria (AKU) causes severe arthritis. Nitisinone reduces the production of HGA, but whether it also decreases arthroplasty was examined in 237 AKU patients. Patients...
3.
Ranganath L, Milan A, Hughes A, Davison A, M K, Norman B, et al.
Sci Rep
. 2022 Sep;
12(1):16083.
PMID: 36167967
Nitisinone (NIT) produces inevitable but varying degree of tyrosinaemia. However, the understanding of the dynamic adaptive relationships within the tyrosine catabolic pathway has not been investigated fully. The objective of...
4.
Ranganath L, Hughes A, Davison A, Khedr M, Olsson B, Rudebeck M, et al.
Mol Genet Metab
. 2022 Jun;
PMID: 35680516
Background: Adaptations within the phenylalanine (PHE)/tyrosine (TYR) pathway during nitisinone (NIT) are not fully understood. Objective: To characterise the temporal changes in metabolic features in NIT-treated patients with alkaptonuria. Patients...
5.
Ranganath L, Milan A, Hughes A, Davison A, Khedr M, Norman B, et al.
Mol Genet Metab Rep
. 2022 Mar;
30:100846.
PMID: 35242577
Background: Although changes in the tyrosine pathway during nitisinone therapy are known, a complete characterization of the induced tyrosinaemia is lacking to improve disease management. Patients And Methods: Our research...
6.
Hardonova M, Siarnik P, Sivakova M, Sucha M, Vlcek M, Imrich R, et al.
Physiol Res
. 2021 Oct;
70(6):875-882.
PMID: 34717060
Autonomic nervous system (ANS) disorders are common in multiple sclerosis (MS). Previous studies showed differences in insulin resistance (IR) and lipoprotein levels in MS subjects compared to controls. Lipolysis caused...
7.
Braconi D, Giustarini D, Marzocchi B, Peruzzi L, Margollicci M, Rossi R, et al.
Osteoarthritis Cartilage
. 2018 Jun;
26(8):1078-1086.
PMID: 29852277
Objective: The aim of this work was to assess baseline serum levels of established biomarkers related to inflammation and oxidative stress in samples from alkaptonuric subjects enrolled in SONIA1 (n ...
8.
Penesova A, Dean Z, Kollar B, Havranova A, Imrich R, Vlcek M, et al.
Physiol Res
. 2018 May;
67(4):521-533.
PMID: 29750884
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. In addition to the genetic, epigenetic and immunological components, various other factors, e.g. unhealthy dietary...
9.
Bajer B, Vlcek M, Galusova A, Imrich R, Penesova A
Endocr Regul
. 2015 Aug;
49(3):151-63.
PMID: 26238498
Obesity management for achieving an effective weight loss includes dietary modification and exercise [resistance (strength), endurance (cardiovascular) or intervals training (high-intensity intermittent exercise)]. Regular exercise acutely increases fat oxidation, which...
10.
Mravcova M, Chovanova L, Paulikova L, Vlcek M, Rovensky J, Killinger Z, et al.
Horm Metab Res
. 2014 Dec;
47(6):411-7.
PMID: 25502945
Inadequate production of cortisol related to inflammation and decrease in adrenal androgen production are hallmarks of hypothalamic-pituitary-adrenal (HPA)-related endocrine findings in rheumatoid arthritis (RA). In particular, lower dehydroepiandrosterone sulfate (DHEAS)...