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R Helme

Explore the profile of R Helme including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 148
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Recent Articles
1.
Wilkinson D, Doody R, Helme R, Taubman K, Mintzer J, Kertesz A, et al.
Neurology . 2003 Aug; 61(4):479-86. PMID: 12939421
Objective: To evaluate the efficacy and tolerability of donepezil in patients with vascular dementia (VaD). Methods: Patients (n = 616; mean age, 75.0 years) with probable or possible VaD, according...
2.
Farrell M, Gibson S, McMEEKEN J, Helme R
J Rheumatol . 2000 Feb; 27(2):441-7. PMID: 10685812
Objective: Tissue damage and pain can lead to a change in the stimulus/response characteristics of the nociceptive system. Hyperalgesia has been described in experimental pain states and some clinical conditions,...
3.
Khalil Z, Helme R
J Gerontol A Biol Sci Med Sci . 1996 Sep; 51(5):B354-61. PMID: 8808984
An intact nociceptor system of primary afferent sensory nerves is important for the initiation of the inflammatory process and successful tissue repair. Dysfunction of this system with age could be...
4.
Khalil Z, Sanderson K, Isberg P, Bassirat M, Livett B, Helme R
Brain Res . 1994 Jul; 651(1-2):227-35. PMID: 7522933
The primary constituent of the senile plaque core in Alzheimer's disease (AD) is the beta-amyloid protein (beta A4). A discrete 11 amino acid fragment of the beta A4, beta A4(25-35),...
5.
Jackson G, Miller M, Littlejohn G, Helme R, KING R
J Rheumatol . 1986 Dec; 13(6):1161-2. PMID: 3560104
The case of a 25-year-old female with bilateral internuclear ophthalmoplegia as a presenting feature of systemic lupus erythematosus (SLE) is described. It is important to recognize that bilateral internuclear ophthalmoplegia...
6.
Jackson B, White D, Cubela R, Helme R
Clin Exp Pharmacol Physiol . 1985 Mar; 12(2):187-91. PMID: 2408805
We have examined the effect of electrical nerve stimulation on substance P and angiotensin converting enzyme activity in the interstitial fluid of rat skin using a blister model. Following sciatic...