R H Quarles
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Explore the profile of R H Quarles including associated specialties, affiliations and a list of published articles.
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167
Citations
2307
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Recent Articles
1.
Ilyas A, Gu Y, Dalakas M, Quarles R, Bhatt S
J Neuroimmunol
. 2007 Nov;
193(1-2):87-93.
PMID: 18037501
IgM paraproteins in about 50% of the patients with neuropathy associated with IgM gammopathy react with carbohydrate moieties in myelin-associated glycoprotein (MAG) and in sulfated glucuronic glycolipids (SGGLs) in human...
2.
Marta C, Taylor C, Cheng S, Quarles R, Bansal R, Pfeiffer S
Neuron Glia Biol
. 2006 Sep;
1(1):35-46.
PMID: 16998591
Myelin-associated glycoprotein (MAG) has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on the apposing axon,...
3.
Quarles R
Cell Mol Life Sci
. 2003 Jan;
59(11):1851-71.
PMID: 12530518
Myelin sheaths are formed around axons by extending, biochemically modifying and spiraling plasma membranes of Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system...
4.
Madhavarao C, Hammer J, Quarles R, Namboodiri M
Anal Biochem
. 2002 Nov;
308(2):314-9.
PMID: 12419345
Recent studies have shown that aspartoacylase (ASPA), the defective enzyme in Canavan disease, is detectable in the brain only in the oligodendrocytes. Studying the regulation of ASPA is central to...
5.
Franzen R, Tanner S, Dashiell S, Rottkamp C, Hammer J, Quarles R
J Cell Biol
. 2001 Dec;
155(6):893-8.
PMID: 11733546
Myelin-associated glycoprotein (MAG) is expressed in periaxonal membranes of myelinating glia where it is believed to function in glia-axon interactions by binding to a component of the axolemma. Experiments involving...
6.
Weiss M, Luciano C, Quarles R
Muscle Nerve
. 2001 Sep;
24(10):1380-7.
PMID: 11562920
Ultrastructural, biochemical, and electrophysiological analyses were done on 12-14-month-old mice deficient for myelin-associated glycoprotein (MAG) to further characterize the neuropathy that develops as they age. Electron microscopy demonstrated normal myelin...
7.
Yim S, Hammer J, Quarles R
J Neurochem
. 2001 Mar;
76(6):1925-34.
PMID: 11259511
Treatment of cultured rat oligodendroglial progenitors with either platelet-derived growth factor (PDGF) or fibroblast growth factor-2 (FGF-2) activated extracellular signal regulated kinase 2 (ERK2). Activation was transient in response to...
8.
Weiss M, Hammer J, Quarles R
J Neurosci Res
. 2000 Dec;
62(6):772-80.
PMID: 11107161
Although MAG-null mice myelinate relatively normally except for subtle structural abnormalities in the periaxonal region of myelin sheaths, they develop more severe pathological changes as they age. The purpose of...
9.
Tanner S, Franzen R, Jaffe H, Quarles R
J Neurochem
. 2000 Jul;
75(2):553-62.
PMID: 10899930
Microtubule-associated protein (MAP) 1B is a high-molecular-weight cytoskeletal protein that is abundant in developing neuronal processes and appears to be necessary for axonal growth. Various biochemical and immunocytochemical results are...
10.
Sasagasako N, Ohno M, Quarles R
Dev Neurosci
. 2000 Jan;
21(6):417-22.
PMID: 10640860
The spontaneously immortalized S16 Schwann cell line expresses higher levels of myelin-associated glycoprotein (MAG) and PO glycoprotein and their messenger RNAs when grown at high density than at low density...