R H Perlis
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Explore the profile of R H Perlis including associated specialties, affiliations and a list of published articles.
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40
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2045
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Recent Articles
1.
Fabbri C, Tansey K, Perlis R, Hauser J, Henigsberg N, Maier W, et al.
Pharmacogenomics J
. 2017 Nov;
18(3):413-421.
PMID: 29160301
Genome-wide association studies have generally failed to identify polymorphisms associated with antidepressant response. Possible reasons include limited coverage of genetic variants that this study tried to address by exome genotyping...
2.
McCoy T, Castro V, Snapper L, Hart K, Januzzi J, Huffman J, et al.
Transl Psychiatry
. 2017 Sep;
7(9):e1238.
PMID: 28926002
Major depressive disorder frequently co-occurs with medical disorders, raising the possibility of shared genetic liability. Recent identification of 15 novel genetic loci associated with depression allows direct investigation of this...
3.
McCoy T, Castro V, Cagan A, Snapper L, Roberson A, Perlis R
Pharmacogenomics J
. 2017 Jul;
18(2):347-350.
PMID: 28696416
Despite the recognition that drug-drug interactions contribute substantially to preventable health-care costs, the prevalence of such interactions related to the cytochrome P450 system in clinical practice remains poorly characterized. This...
4.
Venkatesh K, Castro V, Perlis R, Kaimal A
J Perinatol
. 2017 Jul;
37(9):1003-1009.
PMID: 28682318
Objective: To examine the impact of pharmacologic treatment for depression on obstetric outcomes in women treated for depression during the 2 years prior to pregnancy. Study Design: Observational cohort study...
5.
Bigdeli T, Ripke S, Peterson R, Trzaskowski M, Bacanu S, Abdellaoui A, et al.
Transl Psychiatry
. 2017 Mar;
7(3):e1074.
PMID: 28350396
Major depressive disorder (MDD) is a common, complex psychiatric disorder and a leading cause of disability worldwide. Despite twin studies indicating its modest heritability (~30-40%), extensive heterogeneity and a complex...
6.
Charney A, Ruderfer D, Stahl E, Moran J, Chambert K, Belliveau R, et al.
Transl Psychiatry
. 2017 Jan;
7(1):e993.
PMID: 28072414
We performed a genome-wide association study of 6447 bipolar disorder (BD) cases and 12 639 controls from the International Cohort Collection for Bipolar Disorder (ICCBD). Meta-analysis was performed with prior...
7.
Pavlova B, Perlis R, Mantere O, Sellgren C, Isometsa E, Mitchell P, et al.
Psychol Med
. 2016 Dec;
47(6):1107-1115.
PMID: 27995827
Background: Anxiety disorders are highly prevalent in people with bipolar disorder, but it is not clear how many have anxiety disorders even at times when they are free of major...
8.
Sellgren C, Sheridan S, Gracias J, Xuan D, Fu T, Perlis R
Mol Psychiatry
. 2016 Dec;
22(2):170-177.
PMID: 27956744
Engulfment of synapses and neural progenitor cells (NPCs) by microglia is critical for the development and maintenance of proper brain circuitry, and has been implicated in neurodevelopmental as well as...
9.
Rumshisky A, Ghassemi M, Naumann T, Szolovits P, Castro V, McCoy T, et al.
Transl Psychiatry
. 2016 Oct;
6(10):e921.
PMID: 27754482
The ability to predict psychiatric readmission would facilitate the development of interventions to reduce this risk, a major driver of psychiatric health-care costs. The symptoms or characteristics of illness course...
10.
McCoy T, Castro V, Cagan A, Roberson A, Perlis R
Pharmacogenomics J
. 2016 May;
17(4):382-385.
PMID: 27168099
The cytochrome P450 (CYP450) system of drug-metabolizing enzymes may contribute to individual variation in drug response. We examined prevalence of CYP450 substrates at hospital discharge for patients in two cohorts:...