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R Grahame

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Articles 179
Citations 1506
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Recent Articles
1.
Fikree A, Aktar R, Morris J, Grahame R, Knowles C, Aziz Q
Neurogastroenterol Motil . 2016 Sep; 29(3). PMID: 27683076
Background: Patients with Ehlers-Danlos syndrome-hypermobility type (EDS-HT) have increased prevalence of gastrointestinal (GI) symptoms, particularly reflux and dyspepsia. EDS-HT is associated with dysautonomia, psychopathology, and chronic pain which can be...
2.
Grahame R
S Afr Med J . 2016 Jun; 106(6 Suppl 1):S45-6. PMID: 27245524
The Ehlers-Danlos syndromes (EDSs) were originally described by Ehlers in Denmark and Danlos in Paris in 1898 and 1908, respectively. They had both published individual case studies in which the...
3.
Fikree A, Aktar R, Grahame R, Hakim A, Morris J, Knowles C, et al.
Neurogastroenterol Motil . 2015 Mar; 27(4):569-79. PMID: 25817057
Background: The overlap of unexplained gastrointestinal (GI) and somatic symptoms is well established in patients with functional gastrointestinal disorders (FGID). Joint hypermobility syndrome (JHS) is a non-inflammatory connective tissue disorder...
4.
Mastoroudes H, Giarenis I, Cardozo L, Srikrishna S, Vella M, Robinson D, et al.
Int Urogynecol J . 2013 Feb; 24(9):1553-8. PMID: 23436036
Introduction And Hypothesis: Benign joint hypermobility syndrome (BJHS) is a connective tissue disorder associated with joint hypermobility. BJHS is under-recognised by medical professionals and is poorly managed. The aim of...
5.
Mastoroudes H, Giarenis I, Cardozo L, Srikrishna S, Vella M, Robinson D, et al.
BJOG . 2012 Dec; 120(2):187-192. PMID: 23240798
Objective: To determine whether pelvic organ prolapse (POP) and sexual dysfunction are more severe in women with benign joint hypermobility syndrome (BJHS) than in the normal population. Design: Case-control study....
6.
Dean B, Perrett D, Simmonds H, Grahame R
Br J Clin Pharmacol . 2012 Mar; 1(2):119-27. PMID: 22454898
1 The metabolites of thiopurinol have been investigated in intact human and pig erythrocytes using [6-(14)C]-thiopurinol, high voltage electrophoresis and automated cation exchange chromatography. 2 Pre-incubation of human erythrocytes in...
7.
Davies J, Billings R, Burry H, Panayi G, Gibson T, Grahame R
Proc R Soc Med . 2010 Oct; 70(Suppl 6):34-6. PMID: 20919365
No abstract available.
8.
Mohammed S, Lunniss P, Zarate N, Farmer A, Grahame R, Aziz Q, et al.
Neurogastroenterol Motil . 2010 Jul; 22(10):1085-e283. PMID: 20618831
Background:   Previous studies report an association between joint hypermobility (JHM), as a clinical feature of underlying connective tissue (CT) disorder, and pelvic organ prolapse. However, its association with rectal evacuatory...
9.
Zarate N, Farmer A, Grahame R, Mohammed S, Knowles C, Scott S, et al.
Neurogastroenterol Motil . 2009 Oct; 22(3):252-e78. PMID: 19840271
BACKGROUND Unexplained gastrointestinal (GI) symptoms and joint hypermobility (JHM) are common in the general population, the latter described as benign joint hypermobility syndrome (BJHS) when associated with musculo-skeletal symptoms. Despite...
10.
Gibson T, Grahame R
Ann R Coll Surg Engl . 2009 Mar; 66(6):450. PMID: 19310985
No abstract available.