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R Gottardo

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Articles 12
Citations 246
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Recent Articles
1.
Fiorenza S, Zheng Y, Purushe J, Bock T, Sarthy J, Janssens D, et al.
Nat Commun . 2024 Sep; 15(1):8309. PMID: 39333103
Chimeric antigen receptor-modified T cell (CAR-T) immunotherapy has revolutionised blood cancer treatment. Parsing the genetic underpinnings of T cell quality and CAR-T efficacy is challenging. Transcriptomics inform CAR-T state, but...
2.
Bilel S, Murari M, Pesavento S, Arfe R, Tirri M, Torroni L, et al.
Neurotoxicology . 2023 Jan; 95:83-93. PMID: 36634872
The introduction of the so-called New Psychoactive Substances represents a problem of global concern due to several factors, including multiplicity of structures, poorly known activity, short half-life in the market,...
3.
Pesavento S, Bilel S, Murari M, Gottardo R, Arfe R, Tirri M, et al.
Med Sci Law . 2022 Jan; 62(3):188-198. PMID: 35040690
In an effort to find alternatives to study the so-called New Psychoactive Substances (NPS), the present work was undertaken to investigate the use of zebrafish larvae as animal model in...
4.
Giel-Moloney M, Esteban M, Oakes B, Vaine M, Asbach B, Wagner R, et al.
Sci Rep . 2019 Dec; 9(1):20005. PMID: 31882800
Multiple approaches utilizing viral and DNA vectors have shown promise in the development of an effective vaccine against HIV. In this study, an alternative replication-defective flavivirus vector, RepliVax (RV), was...
5.
Paulson K, Voillet V, McAfee M, Hunter D, Wagener F, Perdicchio M, et al.
Nat Commun . 2018 Sep; 9(1):3868. PMID: 30250229
Understanding mechanisms of late/acquired cancer immunotherapy resistance is critical to improve outcomes; cellular immunotherapy trials offer a means to probe complex tumor-immune interfaces through defined T cell/antigen interactions. We treated...
6.
Monk B, Brady M, Aghajanian C, Lankes H, Rizack T, Leach J, et al.
Ann Oncol . 2017 Apr; 28(5):996-1004. PMID: 28453702
Background: A phase 2, randomized, placebo-controlled trial was conducted in women with recurrent epithelial ovarian carcinoma to evaluate the efficacy and safety of motolimod-a Toll-like receptor 8 (TLR8) agonist that...
7.
Danese E, Fava C, Beltrame F, Tavella D, Calabria S, Benati M, et al.
J Thromb Haemost . 2015 Nov; 14(2):282-93. PMID: 26576037
Unlabelled: ESSENTIALS: The reliability of platelet tests as markers of the variable bioavailability of clopidogrel is not yet defined. Kinetics of clopidogrel active metabolite (CAM) and platelet response were studied...
8.
Dahlberg A, Woo S, Delaney C, Boyle P, Gnirke A, Bock C, et al.
Leukemia . 2015 Mar; 29(9):1948-51. PMID: 25742749
No abstract available.
9.
Tennant B, Robertson A, Kramer M, Li L, Zhang X, Beach M, et al.
Diabetologia . 2012 Dec; 56(3):542-52. PMID: 23238790
Aims/hypothesis: The paucity of information on the epigenetic barriers that are blocking reprogramming protocols, and on what makes a beta cell unique, has hampered efforts to develop novel beta cell...
10.
Bortolotti F, Gottardo R, Pascali J, Tagliaro F
Curr Med Chem . 2012 Aug; 19(33):5658-63. PMID: 22856660
Cocaine is one of the most used psychomotor stimulants all over the world. On this basis, the interest for the pharmacological activity and the pharmacodynamic and pharmacokinetic aspects of this...