R G Tompkins
Overview
Explore the profile of R G Tompkins including associated specialties, affiliations and a list of published articles.
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Articles
208
Citations
3911
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Recent Articles
1.
Cuenca A, Maier R, Cuschieri J, Moore E, Moldawer L, Tompkins R
Eur J Trauma Emerg Surg
. 2016 Jan;
37(6):549-58.
PMID: 26815465
Despite ongoing improvements in resuscitation, care, and outcomes, traumatic injury remains a significant health care and economic burden. The causes are multifactorial, but our approach to the clinical management of...
2.
Goverman J, Montecino R, Ibrahim A, Sarhane K, Tompkins R, Fagan S
Ann Burns Fire Disasters
. 2015 Jul;
27(3):146-50.
PMID: 26170794
This report describes a case of burn injury following exposure to sulfur mustard, a chemical agent used in war. A review of the diagnostic characteristics, clinical manifestations, and therapeutic measures...
3.
Lu X, Tompkins R, Fischman A
Int J Mol Med
. 2013 Jan;
31(3):740-50.
PMID: 23314241
Severe burn injury is an acute inflammatory state with massive alterations in gene expression and levels of growth factors, cytokines and free radicals. During the catabolic processes, changes in insulin...
4.
Lu X, Tompkins R, Fischman A
Int J Mol Med
. 2011 Dec;
29(3):461-71.
PMID: 22179310
Akt1/protein kinase Bα (Akt1/PKBα) is a downstream mediator of the insulin signaling system. In this study we explored mechanism(s) for its role in burn injury. Akt1/PKBα in liver extracts from...
5.
Berthiaume F, Tompkins R, Yarmush M
Methods Mol Med
. 2011 Mar;
18:447-56.
PMID: 21370195
Long-term and stable hepatocyte culture systems have a wide variety of uses, both in basic science and in the development of hepatocyte-based applications. In most cases, long-term cultures of hepatocytes...
6.
Rotem A, Matthew H, Hsiao P, Toner M, Tompkins R, Yarmush M
Toxicol In Vitro
. 2010 Jul;
9(2):139-49.
PMID: 20650073
In this study, a stable, differentiated culture format (primary hepatocytes cultured between two layers of collagen gel) was used to study the effect of the inducer 3,3',4,4'-tetrachlorobiphenyl (TCB) on the...
7.
Huang R, Barber T, Schmidt M, Tompkins R, Toner M, Bianchi D, et al.
Prenat Diagn
. 2008 Sep;
28(10):892-9.
PMID: 18821715
Objective: Nucleated red blood cells (NRBCs) have been identified in maternal circulation and potentially provide a resource for the monitoring and diagnosis of maternal, fetal, and neonatal health and disease....
8.
Washizu J, Berthiaume F, Mokuno Y, Tompkins R, Toner M, Yarmush M
Tissue Eng
. 2001 Dec;
7(6):691-703.
PMID: 11749727
Little information on the effect of plasma on hepatocyte cytochrome P450 (CYP) activities is currently available. We characterized the effect of plasma on CYPs of hepatocyte-mesenchymal cell co-cultures, which exhibit...
9.
Shito M, Balis U, Tompkins R, Yarmush M, Toner M
Dig Dis Sci
. 2001 Aug;
46(8):1700-8.
PMID: 11508670
The development of a fulminant hepatic failure (FHF) model is necessary for evaluating the efficacy of extracorporeal liver support systems. Recognizing the multifaceted functions of the liver, including synthesis and...
10.
Sheridan R, Weber J, Pasternack M, Tompkins R
J Trauma
. 2001 Aug;
51(2):352-5.
PMID: 11493799
Background: Historically, group A beta-hemolytic streptococci (GAS) burn wound infection has been a major source of morbidity and mortality in burn patients and has prompted the prophylactic administration of antibiotics...