R E Seftor
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Explore the profile of R E Seftor including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1874
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Recent Articles
1.
Hendrix M, Seftor E, Seftor R
Methods Mol Med
. 2011 Feb;
58:71-9.
PMID: 21340849
Metastasis is the major cause of morbidity and death for cancer patients. A critical challenge to clinical and basic scientists is the development of improved prognostic methods to predict the...
2.
Seftor R, Stamer W, Seftor E, Snyder R
J Glaucoma
. 2009 Nov;
3(4):323-8.
PMID: 19920617
Previously, we observed that dexamethasone decreased the extracellular activity of some matrix metalloproteinases and tissue plasminogen activator in trabecular meshwork containing organ explants and cell cultures. We have extended these...
3.
Seftor R, Seftor E, Koshikawa N, Meltzer P, Gardner L, Bilban M, et al.
Cancer Res
. 2001 Aug;
61(17):6322-7.
PMID: 11522618
Vasculogenic mimicry describes a process where aggressive tumor cells in three-dimensional matrices mimic embryonic vasculogenesis by forming extracellular matrix (ECM)-rich, patterned tubular networks. Microarray gene chip analyses revealed significant increases...
4.
Hendrix M, Seftor E, Meltzer P, Gardner L, HESS A, Kirschmann D, et al.
Proc Natl Acad Sci U S A
. 2001 Jun;
98(14):8018-23.
PMID: 11416160
We recently have introduced the term vasculogenic mimicry to describe the unique ability of aggressive melanoma tumor cells to form tubular structures and patterned networks in three-dimensional culture, which "mimics"...
5.
HESS A, Seftor E, Gardner L, Schneider G, Seftor R, Kinch M, et al.
Cancer Res
. 2001 Apr;
61(8):3250-5.
PMID: 11309274
During embryogenesis, blood vessels are formed initially by the process of vasculogenesis, the in situ differentiation of mesenchymal cells into endothelial cells, which form a primitive, patterned vasculogenic network. This...
6.
Sood A, Seftor E, Fletcher M, Gardner L, Heidger P, Buller R, et al.
Am J Pathol
. 2001 Apr;
158(4):1279-88.
PMID: 11290546
During development, the formation and remodeling of primary vascular networks occurs by vasculogenesis and angiogenesis. Recently, the term "vasculogenic mimicry" has been used by our laboratory and collaborators to reflect...
7.
Hendrix M, Seftor E, Kirschmann D, Seftor R
Breast Cancer Res
. 2001 Mar;
2(6):417-22.
PMID: 11250735
During embryogenesis, the formation of primary vascular networks occurs via the processes of vasculogenesis and angiogenesis. In uveal melanoma, vasculogenic mimicry describes the 'embryonic-like' ability of aggressive, but not nonaggressive,...
8.
Seftor R, Seftor E, Hendrix M
Cancer Metastasis Rev
. 2000 Mar;
18(3):359-75.
PMID: 10721490
There are fundamental issues regarding the role of integrins in human disease which remain to be elucidated. Human cutaneous melanoma is an attractive model for studying integrin involvement in tumor...
9.
Seftor E, Seftor R, Nieva D, Hendrix M
Adv Dent Res
. 1999 Feb;
12(2):103-10.
PMID: 9972131
No abstract available.
10.
Seftor R, Seftor E, Sheng S, PEMBERTON P, Sager R, Hendrix M
Cancer Res
. 1998 Dec;
58(24):5681-5.
PMID: 9865722
The recently discovered tumor suppressor gene maspin has been shown to inhibit tumor cell motility, invasion, and metastasis in breast cancer by our laboratories. Nonetheless, the exploitation of maspin as...