R E Heikkila
Overview
Explore the profile of R E Heikkila including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
2041
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Recent Articles
1.
Giovanni A, Sonsalla P, Heikkila R
J Pharmacol Exp Ther
. 1994 Sep;
270(3):1008-14.
PMID: 7932148
There are marked species differences in susceptibility to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Mice are sensitive, whereas rats are relatively insensitive to MPTP. In these two species, the effects...
2.
Giovanni A, Sieber B, Heikkila R, Sonsalla P
J Pharmacol Exp Ther
. 1994 Sep;
270(3):1000-7.
PMID: 7932147
Several parameters necessary for the expression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity to dopaminergic neurons were examined in both mice and rats in order to determine if differences in these processes might...
3.
Mark M, Sage J, Dickson D, Heikkila R, Manzino L, Schwarz K, et al.
Neurology
. 1994 Aug;
44(8):1432-6.
PMID: 8058144
We report a patient with Meige syndrome (segmental cranial dystonia) who had neuropathologic changes of Parkinson's disease on postmortem examination. Neuropathologic examination showed typical and atypical Lewy bodies in the...
4.
SINGER T, Ramsay R, Sonsalla P, Nicklas W, Heikkila R
Adv Neurol
. 1993 Jan;
60:300-5.
PMID: 8380523
No abstract available.
5.
Terleckyj I, Heikkila R
Ann N Y Acad Sci
. 1992 May;
648:365-7.
PMID: 1637071
No abstract available.
6.
Nicklas W, Saporito M, Basma A, Geller H, Heikkila R
Ann N Y Acad Sci
. 1992 May;
648:28-36.
PMID: 1637057
No abstract available.
7.
Basma A, Heikkila R, Saporito M, Philbert M, Geller H, Nicklas W
J Neurochem
. 1992 Mar;
58(3):1052-9.
PMID: 1737983
The effects of 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine (2'Et-MPTP), 1-methyl-4-(2'-ethylphenyl)pyridinium (2'Et-MPP+), and the classic complex 1 inhibitor, rotenone, on toxicity as well as on rates of glucose use and lactate production were studied using...
8.
Heikkila R, Sonsalla P
Neurochem Int
. 1992 Mar;
20 Suppl:299S-303S.
PMID: 1365446
No abstract available.
9.
Saporito M, Heikkila R, Youngster S, Nicklas W, Geller H
J Pharmacol Exp Ther
. 1992 Mar;
260(3):1400-9.
PMID: 1312170
Several analogs of 1-methyl-4-phenylpyridinium (MPP+) were evaluated for their affinity for the dopamine uptake system and their ability to inhibit NADH dehydrogenase (complex I) of the mitochondrial electron-transport chain. Moreover,...
10.
Giovanni A, Sieber B, Heikkila R, Sonsalla P
J Pharmacol Exp Ther
. 1991 May;
257(2):691-7.
PMID: 2033514
In the present study we observed pronounced differences in the capacity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to induce dopaminergic neurotoxicity in several strains of mice. For example, there was no MPTP-induced decrement...