R D Cox
Overview
Explore the profile of R D Cox including associated specialties, affiliations and a list of published articles.
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Articles
84
Citations
1414
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Recent Articles
1.
Al-Dibouni A, Gaspar R, Ige S, Boateng S, Cagampang F, Gibbins J, et al.
Nutrients
. 2020 Jun;
12(6).
PMID: 32580292
Obesity is a major risk factor for a plethora of metabolic disturbances including diabetes and cardiovascular disease. Accumulating evidence is showing that there is an adipose tissue depot-dependent relationship with...
2.
Xi L, De Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa C, et al.
Bone
. 2019 Nov;
131:115111.
PMID: 31726107
As bone is used in a dynamic mechanical environment, understanding the structural origins of its time-dependent mechanical behaviour - and the alterations in metabolic bone disease - is of interest....
3.
Xi L, De Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa C, et al.
Acta Biomater
. 2018 Jun;
76:295-307.
PMID: 29902593
Significance Statement: Increased fragility in musculoskeletal disorders like osteoporosis are believed to arise due to alterations in bone structure at multiple length-scales from the organ down to the supramolecular-level, where...
4.
Karunaratne A, Xi L, Bentley L, Sykes D, Boyde A, Esapa C, et al.
Bone
. 2015 Dec;
84:15-24.
PMID: 26657825
A serious adverse clinical effect of glucocorticoid steroid treatment is secondary osteoporosis, enhancing fracture risk in bone. This rapid increase in bone fracture risk is largely independent of bone loss...
5.
Karunaratne A, Boyde A, Esapa C, Hiller J, Terrill N, Brown S, et al.
Bone
. 2012 Nov;
52(2):689-98.
PMID: 23128355
In metabolic bone diseases, the alterations in fibrillar level bone-material quality affecting macroscopic mechanical competence are not well-understood quantitatively. Here, we quantify the fibrillar level deformation in cantilever bending in...
6.
Karunaratne A, Davis G, Hiller J, Esapa C, Terrill N, Brown S, et al.
Bone
. 2012 May;
51(3):553-62.
PMID: 22609228
Metabolic bone disorders such as rickets are associated with altered in vivo muscular force distributions on the skeletal system. During development, these altered forces can potentially affect the spatial and...
7.
8.
Hugill A, Shimomura K, Ashcroft F, Cox R
Diabetologia
. 2010 Aug;
53(11):2352-6.
PMID: 20694718
Aims/hypothesis: We identified a mouse with a point mutation (Y12STOP) in the Kcnj11 subunit of the K(ATP) channel. This point mutation is identical to that found in a patient with...
9.
Kelly M, Moir L, Jones L, Whitehill E, Anstee Q, Goldin R, et al.
Int J Obes (Lond)
. 2009 Feb;
33(5):507-18.
PMID: 19238158
Objective: The Gnas transcription unit located within an imprinting region encodes several proteins, including the G-protein alpha-subunit, Gsalpha, its isoform XLalphas and their variant truncated neural forms GsalphaN1 and XLN1....
10.
Salek R, Maguire M, Bentley E, Rubtsov D, Hough T, Cheeseman M, et al.
Physiol Genomics
. 2006 Dec;
29(2):99-108.
PMID: 17190852
Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target tissues. There are an estimated 150 million affected individuals worldwide,...