R C Pirola
Overview
Explore the profile of R C Pirola including associated specialties, affiliations and a list of published articles.
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Articles
75
Citations
1418
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Recent Articles
1.
Apte M, Xu Z, Pothula S, Goldstein D, Pirola R, Wilson J
Pancreatology
. 2015 Apr;
15(4 Suppl):S32-8.
PMID: 25845856
The abundant stromal/desmoplastic reaction, a characteristic feature of a majority of pancreatic adenocarcinomas (PDAC), has only recently been receiving some attention regarding its possible role in the pathobiology of pancreatic...
2.
Apte M, Pirola R, Wilson J
Dig Dis
. 2006 Mar;
23(3-4):232-40.
PMID: 16508287
Alcoholic pancreatitis is a major complication of alcohol abuse. Since only a minority of alcoholics develop pancreatitis, there has been a keen interest in identifying the factors that may confer...
3.
McCarroll J, Phillips P, Santucci N, Pirola R, Wilson J, Apte M
Gut
. 2005 Jul;
55(1):79-89.
PMID: 16043492
Background And Aims: Activated pancreatic stellate cells (PSCs) are implicated in the production of alcohol induced pancreatic fibrosis. PSC activation is invariably associated with loss of cytoplasmic vitamin A (retinol)...
4.
5.
McCarroll J, Phillips P, Park S, Doherty E, Pirola R, Wilson J, et al.
Pancreas
. 2003 Jul;
27(2):150-60.
PMID: 12883264
Background: Pancreatic fibrosis is a characteristic feature of alcoholic chronic pancreatitis. Recent studies suggest that activated pancreatic stellate cells (PSCs) are the major cell-type involved in pancreatic fibrogenesis. Cultured PSCs...
6.
Phillips P, Wu M, Kumar R, Doherty E, McCarroll J, Park S, et al.
Gut
. 2003 Apr;
52(5):677-82.
PMID: 12692052
Background: Pancreatic stellate cells (PSCs), implicated as key mediators of pancreatic fibrogenesis, are found in increased numbers in areas of pancreatic injury. This increase in PSC number may be due...
7.
Haber P, Nakamura M, Tsuchimoto K, Keogh G, Apte M, Moran C, et al.
Alcohol Clin Exp Res
. 2001 Jun;
25(5 Suppl ISBRA):244S-250S.
PMID: 11391078
This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan. The presentations were (1) Phenotypic alteration of myofibroblast during ethanol-induced pancreatic injury: its relation...
8.
Apte M, Phillips P, Fahmy R, Darby S, Rodgers S, McCaughan G, et al.
Gastroenterology
. 2000 Mar;
118(4):780-94.
PMID: 10734030
Background & Aims: Activated pancreatic stellate cells have recently been implicated in pancreatic fibrogenesis. This study examined the role of pancreatic stellate cells in alcoholic pancreatic fibrosis by determining whether...
9.
Haber P, Keogh G, Apte M, Moran C, Stewart N, Crawford D, et al.
Am J Pathol
. 1999 Oct;
155(4):1087-95.
PMID: 10514391
The mechanisms of pancreatic fibrosis are poorly understood. In the liver, stellate cells play an important role in fibrogenesis. Similar cells have recently been isolated from the pancreas and are...
10.
Haber P, Norris M, Apte M, Rodgers S, Norton I, Pirola R, et al.
Alcohol Clin Exp Res
. 1999 Apr;
23(3):509-12.
PMID: 10195826
Background: The observation that only a minority of alcoholics develops clinical pancreatic disease has led to a search for a predisposing factor to the disease. One possible predisposing factor is...