R C Aguiar
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Explore the profile of R C Aguiar including associated specialties, affiliations and a list of published articles.
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25
Citations
419
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Recent Articles
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2.
Aguiar R, Cox G, Pomeroy S, Dahia P
J Clin Endocrinol Metab
. 2001 Jun;
86(6):2890-4.
PMID: 11397905
Pheochromocytomas are neural crest-derived tumors that occur mostly sporadically, but may also be part of inherited syndromes. The molecular pathogenesis of sporadic pheochromocytomas remains unknown. Recently, the susceptibility gene for...
3.
Aguiar R, Yakushijin Y, Kharbanda S, Salgia R, Fletcher J, Shipp M
Blood
. 2000 Dec;
96(13):4328-34.
PMID: 11110709
Clinical risk factor models such as the International Prognostic Index are used to identify diffuse large B-cell lymphoma (DLB-CL) patients with different risks of death from their diseases. To elucidate...
4.
Aguiar R, Yakushijin Y, Kharbanda S, Tiwari S, Freeman G, Shipp M
Blood
. 1999 Sep;
94(7):2403-13.
PMID: 10498613
Protein tyrosine phosphatases (PTP) regulate the proliferation, differentiation, and viability of lymphocytes by modulating their signaling pathways. By using the differential display assay, we have cloned a putative receptor-type PTP,...
5.
Carapeti M, Aguiar R, Watmore A, Goldman J, Cross N
Cancer Genet Cytogenet
. 1999 Aug;
113(1):70-2.
PMID: 10459350
We have recently cloned the inv(8)(p11q13) in a patient with acute myeloid leukemia (AML), and demonstrated a fusion between the MOZ and TIF2 genes at 8p11 and 8q13, respectively. We...
6.
Dahia P, Aguiar R, Alberta J, Kum J, Caron S, Sill H, et al.
Hum Mol Genet
. 1999 Feb;
8(2):185-93.
PMID: 9931326
PTEN is a novel tumour suppressor gene that encodes a dual-specificity phosphatase with homology to adhesion molecules tensin and auxillin. It recently has been suggested that PTEN dephosphorylates phosphatidylinositol 3,4,5-trisphosphate...
7.
Carapeti M, Aguiar R, Chase A, Goldman J, Cross N
Genomics
. 1998 Oct;
52(2):242-4.
PMID: 9782096
No abstract available.
8.
Carapeti M, Aguiar R, Sill H, Goldman J, Cross N
Br J Cancer
. 1998 Sep;
78(5):601-5.
PMID: 9744498
Deletions and apparent transcriptional abnormalities of the FHIT gene at 3p14.2 have recently been reported in a wide variety of solid tumours. To determine whether lesions of this gene also...
9.
Reiter A, Sohal J, Kulkarni S, Chase A, MacDONALD D, Aguiar R, et al.
Blood
. 1998 Aug;
92(5):1735-42.
PMID: 9716603
The 8p11 myeloproliferative syndrome is a rare, aggressive condition associated with reciprocal translocations of chromosome band 8p11, most commonly the t(8;13)(p11;q12). To identify the genes involved in this translocation, we...
10.
Aguiar R
Leuk Lymphoma
. 1998 Jun;
29(1-2):17-26.
PMID: 9638972
Second primary cancers represent an important complication of modern chemotherapy and radiotherapy. Therapy-related (tr) leukemias are among the most common second malignancies in both pediatric and adult populations. Whereas a...