R Burke Squires
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Explore the profile of R Burke Squires including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
1052
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Recent Articles
1.
Kumar K, Srinivasan P, Nold M, Moch J, Reiter K, Sturdevant D, et al.
Sci Rep
. 2017 Dec;
7(1):17146.
PMID: 29215067
The symptoms of malaria are brought about by blood-stage parasites, which are established when merozoites invade human erythrocytes. Our understanding of the molecular events that underpin erythrocyte invasion remains hampered...
2.
Parra G, Squires R, Karangwa C, Johnson J, Lepore C, Sosnovtsev S, et al.
PLoS Pathog
. 2017 Jan;
13(1):e1006136.
PMID: 28103318
Noroviruses are major pathogens associated with acute gastroenteritis worldwide. Their RNA genomes are diverse, with two major genogroups (GI and GII) comprised of at least 28 genotypes associated with human...
3.
Pirtskhalava M, Gabrielian A, Cruz P, Griggs H, Squires R, Hurt D, et al.
Nucleic Acids Res
. 2016 Apr;
44(13):6503.
PMID: 27060142
No abstract available.
4.
Hoenen T, Groseth A, Rosenke K, Fischer R, Hoenen A, Judson S, et al.
Emerg Infect Dis
. 2016 Jan;
22(2):331-4.
PMID: 26812583
Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers...
5.
Pirtskhalava M, Gabrielian A, Cruz P, Griggs H, Squires R, Hurt D, et al.
Nucleic Acids Res
. 2015 Nov;
44(D1):D1104-12.
PMID: 26578581
Antimicrobial peptides (AMPs) are anti-infectives that may represent a novel and untapped class of biotherapeutics. Increasing interest in AMPs means that new peptides (natural and synthetic) are discovered faster than...
6.
Deans A, Lewis S, Huala E, Anzaldo S, Ashburner M, Balhoff J, et al.
PLoS Biol
. 2015 Jan;
13(1):e1002033.
PMID: 25562316
Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable...
7.
Squires R, Pickett B, Das S, Scheuermann R
Infect Genet Evol
. 2014 Jul;
28:351-7.
PMID: 25064525
In 2009 a novel pandemic H1N1 influenza virus (H1N1pdm09) emerged as the first official influenza pandemic of the 21st century. Early genomic sequence analysis pointed to the swine origin of...
8.
Dugan V, Emrich S, Giraldo-Calderon G, Harb O, Newman R, Pickett B, et al.
PLoS One
. 2014 Jun;
9(6):e99979.
PMID: 24936976
High throughput sequencing has accelerated the determination of genome sequences for thousands of human infectious disease pathogens and dozens of their vectors. The scale and scope of these data are...
9.
Noronha J, Liu M, Squires R, Pickett B, Hale B, Air G, et al.
J Virol
. 2012 Mar;
86(10):5857-66.
PMID: 22398283
Genetic drift of influenza virus genomic sequences occurs through the combined effects of sequence alterations introduced by a low-fidelity polymerase and the varying selective pressures experienced as the virus migrates...
10.
Squires R, Noronha J, Hunt V, Garcia-Sastre A, Macken C, Baumgarth N, et al.
Influenza Other Respir Viruses
. 2012 Jan;
6(6):404-16.
PMID: 22260278
Background: The recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about...