R A Padgett
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Explore the profile of R A Padgett including associated specialties, affiliations and a list of published articles.
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37
Citations
2769
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Recent Articles
1.
Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway H, et al.
Leukemia
. 2017 Nov;
32(3):839-843.
PMID: 29099495
No abstract available.
2.
Kurtovic-Kozaric A, Przychodzen B, Singh J, Konarska M, Clemente M, Otrock Z, et al.
Leukemia
. 2014 May;
29(1):126-36.
PMID: 24781015
Mutations of spliceosome components are common in myeloid neoplasms. One of the affected genes, PRPF8, encodes the most evolutionarily conserved spliceosomal protein. We identified either recurrent somatic PRPF8 mutations or...
3.
Dietrich R, Shukla G, Fuller J, Padgett R
RNA
. 2001 Oct;
7(10):1378-88.
PMID: 11680842
Alternative splicing increases the coding capacity of genes through the production of multiple protein isoforms by the conditional use of splice sites and exons. Many alternative splice sites are regulated...
4.
Dietrich R, Peris M, Seyboldt A, Padgett R
Mol Cell Biol
. 2001 Mar;
21(6):1942-52.
PMID: 11238930
U12-dependent introns containing alterations of the 3' splice site AC dinucleotide or alterations in the spacing between the branch site and the 3' splice site were examined for their effects...
5.
Shukla G, Padgett R
RNA
. 2001 Feb;
7(1):94-105.
PMID: 11214185
The U6 spliceosomal snRNA forms an intramolecular stem-loop structure during spliceosome assembly that is required for splicing and is proposed to be at or near the catalytic center of the...
6.
Shukla G, Padgett R
RNA
. 1999 Apr;
5(4):525-38.
PMID: 10199569
Splicing of U12-dependent introns requires the function of U11, U12, U6atac, U4atac, and U5 snRNAs. Recent studies have suggested that U6atac and U12 snRNAs interact extensively with each other, as...
7.
Burge C, Padgett R, Sharp P
Mol Cell
. 1999 Jan;
2(6):773-85.
PMID: 9885565
U2-type and U12-type introns are spliced by distinct spliceosomes in eukaryotic nuclei. A classification method was devised to distinguish these two types of introns based on splice site sequence properties...
8.
Podar M, Perlman P, Padgett R
RNA
. 1998 Aug;
4(8):890-900.
PMID: 9701281
The two transesterification reactions catalyzed by self-splicing group II introns take place in either two active sites or two conformations of a single active site involving rearrangements of the positions...
9.
Dietrich R, Incorvaia R, Padgett R
Mol Cell
. 1998 Jul;
1(1):151-60.
PMID: 9659912
Two types of eukaryotic nuclear introns are known: the common U2-dependent class with /GU and AG/ terminal intron dinucleotides, and the rare U12-dependent class with /AU and AC/ termini. Here...
10.
Incorvaia R, Padgett R
RNA
. 1998 Jun;
4(6):709-18.
PMID: 9622129
The minor U12-dependent class of eukaryotic nuclear pre-mRNA introns is spliced by a distinct spliceosomal mechanism that requires the function of U11, U12, U5, U4atac, and U6atac snRNAs. Previous work...