R A Nichols
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Explore the profile of R A Nichols including associated specialties, affiliations and a list of published articles.
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70
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1109
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Recent Articles
11.
Overall A, Ahmad M, Thomas M, Nichols R
Ann Hum Genet
. 2003 Dec;
67(Pt 6):525-37.
PMID: 14641240
We analysed microsatellite genotypes sampled from the Pakistani and Indian communities in Nottingham, UK, to investigate the genetic consequences of substructuring mediated by traditional marriage customs. The application of a...
12.
Overall A, Ahmad M, Nichols R
Heredity (Edinb)
. 2002 Aug;
88(6):474-9.
PMID: 12180090
We investigate the effects of consanguinity and population substructure on genetic health using the UK Asian population as an example. We review and expand upon previous treatments dealing with the...
13.
A method for distinguishing consanguinity and population substructure using multilocus genotype data
Overall A, Nichols R
Mol Biol Evol
. 2001 Oct;
18(11):2048-56.
PMID: 11606701
We use the patterns of homozygosity at multiple loci to distinguish between excess homozygosity caused by consanguineous mating and that due to undetected population subdivision (the Wahlund effect). Clarification of...
14.
Paulo O, Dias C, Bruford M, Jordan W, Nichols R
Proc Biol Sci
. 2001 Aug;
268(1476):1625-30.
PMID: 11487410
Ancient climatic fluctuations have caused changes in the demography and distribution of many species. The genetic differentiation between populations of the same species and of sister species is often attributed...
15.
Wilcock H, Hildrew A, Nichols R
Mol Ecol
. 2001 Jul;
10(7):1821-34.
PMID: 11472549
We describe the genetic structure of a freshwater insect species and interpret it in terms of present-day population dynamics and possible postglacial colonization history. The sampling regime represented a large...
16.
Burland T, Barratt E, Nichols R, Racey P
Mol Ecol
. 2001 May;
10(5):1309-21.
PMID: 11380886
The brown long-eared bat, Plecotus auritus, is unusual among temperate zone bats in that summer maternity colonies are composed of adult males and females, with both sexes displaying natal philopatry...
17.
Saccheri I, Nichols R, Brakefield P
Genet Res
. 2001 May;
77(2):167-81.
PMID: 11355572
The effects of a single population bottleneck of differing severity on heritability and additive genetic variance was investigated experimentally using a butterfly. An outbred laboratory stock was used to found...
18.
Nichols R, Bruford M, Groombridge J
Mol Ecol
. 2001 Apr;
10(3):593-602.
PMID: 11298971
We obtained measures of genetic diversity in 10 kestrel species at a suite of 12 microsatellite loci. We estimated the relative effective size (Ne) of the species using a Markov...
19.
Nayak S, Dougherty J, McIntosh J, Nichols R
J Neurochem
. 2001 Mar;
76(6):1860-70.
PMID: 11259504
Presynaptic nicotinic acetylcholine receptors likely play a modulatory role in the nerve terminal. Using laser-scanning confocal microscopy, we have characterized physiological responses obtained on activation of presynaptic nicotinic receptors by...
20.
Ronde P, Nichols R
Neuroscience
. 2001 Feb;
102(4):979-87.
PMID: 11182259
Rat brain presynaptic 5-HT3 serotonin receptors, members of the ligand-gated ion channel superfamily, induce changes in nerve terminal [Ca2+]i in a manner distinct from that found for somatic 5-HT3 receptors....