R A Moorehead
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Explore the profile of R A Moorehead including associated specialties, affiliations and a list of published articles.
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21
Citations
748
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Recent Articles
1.
Simpson K, Conquer-van Heumen G, Watson K, Roth M, Martin C, Moorehead R
Cancer Cell Int
. 2021 Feb;
21(1):89.
PMID: 33541373
Background: MicroRNAs are a class of non-coding RNAs that regulate gene expression through binding to mRNAs and preventing their translation. One family of microRNAs known as the miR-200 family is...
2.
Saleh S, Thompson D, McConkey J, Murray P, Moorehead R
BMC Cancer
. 2016 Jun;
16:359.
PMID: 27282619
Background: Osteopontin is a secreted phosphoglycoprotein that is expressed by a number of normal cells as well as a variety of tumor cells. With respect to breast cancer, osteopontin has...
3.
Khadim M, Leonard D, Moorehead R, Hill C
Ann R Coll Surg Engl
. 2013 Oct;
95(7):110-1.
PMID: 24112480
We present a case of distal venous embolisation of a peripheral intravenous cannula tip that had lost its structural integrity through repeated failed attempts of insertion of the same cannula,...
4.
Franks S, Campbell C, Barnett E, Siwicky M, Livingstone J, Cory S, et al.
Oncogene
. 2011 Oct;
31(27):3298-309.
PMID: 22020329
Molecular profiling has allowed a more precise classification of human cancers. With respect to breast cancer, this approach has been used to identify five subtypes; luminal A, luminal B, HER2-enriched,...
5.
Campbell N, Kellenberger L, Greenaway J, Moorehead R, Linnerth-Petrik N, Petrik J
J Oncol
. 2010 Jul;
2010:586905.
PMID: 20671917
Tumor development is a complex process that relies on interaction and communication between a number of cellular compartments. Much of the mass of a solid tumor is comprised of the...
6.
Jones R, Petrik J, Moorehead R
Oncogene
. 2010 Jun;
29(34):4779-86.
PMID: 20543862
Despite our incomplete understanding of the function of the type I insulin-like growth factor receptor (IGF-IR) in tumorigenesis, IGF-IR targeting agents have entered clinical trials for the treatment of human...
7.
Kellenberger L, Bruin J, Greenaway J, Campbell N, Moorehead R, Holloway A, et al.
J Oncol
. 2010 Feb;
2010:514310.
PMID: 20182531
Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer and also one of the most poorly understood. Other health issues that are affecting women with increasing frequency are obesity...
8.
Jones R, Campbell C, Wood G, Petrik J, Moorehead R
Oncogene
. 2009 Apr;
28(21):2152-62.
PMID: 19377512
The type-I insulin-like growth factor receptor (IGF-IR) is frequently overexpressed in breast cancer and therapeutic agents targeting IGF-IR are currently in development. The ultimate success of anti-IGF-IR therapies will depend...
9.
Linnerth N, Greenaway J, Petrik J, Moorehead R
Int J Gynecol Cancer
. 2008 Jun;
18(6):1248-57.
PMID: 18554190
Approximately 90% of human ovarian tumors result from transformation of ovarian surface epithelial cells. It has been hypothesized that repeated destruction of the epithelial cells during ovulation, followed by proliferation...
10.
Jones R, Campbell C, Gunther E, Chodosh L, Petrik J, Khokha R, et al.
Oncogene
. 2006 Sep;
26(11):1636-44.
PMID: 16953219
Overexpression and hyperactivation of the type I insulin-like growth factor receptor (IGF-IR) has been observed in human breast tumor biopsies. In addition, in vitro studies indicate that overexpression of IGF-IR...