R A F MacLeod
Overview
Explore the profile of R A F MacLeod including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
600
Followers
0
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Related Specialties
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Recent Articles
1.
MacLeod R, Schneider B, Sivakova I, Nagel S, Dirks W, Mraz P, et al.
Neoplasma
. 2018 Dec;
66(1):109-117.
PMID: 30509096
Glioblastoma multiforme is a highly invasive and incurable primary brain tumor. The most frequent genetic alteration therein is amplification of the epidermal growth factor receptor (EGFR) gene, the target of...
2.
Pommerenke C, Hauer V, Zaborski M, MacLeod R, Nagel S, Amini R, et al.
Blood Cancer J
. 2016 Jun;
6:e433.
PMID: 27284737
No abstract available.
3.
Kreck B, Richter J, Ammerpohl O, Barann M, Esser D, Petersen B, et al.
Leukemia
. 2013 Jan;
27(8):1751-3.
PMID: 23307032
No abstract available.
4.
Quentmeier H, Amini R, Berglund M, Dirks W, Ehrentraut S, Geffers R, et al.
Leukemia
. 2013 Jan;
27(5):1155-64.
PMID: 23295736
Genetic heterogeneity is common in tumors, explicable by the development of subclones with distinct genetic and epigenetic alterations. We describe an in vitro model for cancer heterogeneity, comprising the diffuse...
5.
Chen S, Nagel S, Schneider B, Kaufmann M, Meyer C, Zaborski M, et al.
Leukemia
. 2011 Jun;
25(10):1632-5.
PMID: 21647158
No abstract available.
6.
Suzuki S, Nagel S, Schneider B, Chen S, Kaufmann M, Uozumi K, et al.
Leukemia
. 2009 Jan;
23(5):1003-6.
PMID: 19151773
No abstract available.
7.
Quentmeier H, Geffers R, Jost E, MacLeod R, Nagel S, Rohrs S, et al.
Leukemia
. 2008 Sep;
22(12):2169-75.
PMID: 18769447
Janus kinase 2 (JAK2)V617F-activating mutations (JAK2mu) occur in myeloproliferative disorders (MPDs) and myelodysplastic syndromes (MDSs). Cell lines MB-02, MUTZ-8, SET-2 and UKE-1 carry JAK2V617F and derive from patients with MPD/MDS...
8.
Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler H, MacLeod R
Leukemia
. 2007 Dec;
22(3):600-7.
PMID: 18079734
In T-cell acute lymphoblastic leukemia (T-ALL) the cardiac homeobox gene NKX2-5 (at 5q35) is variously deregulated by regulatory elements coordinating with BCL11B (at 14q32.2), or the T-cell receptor gene TRD...
9.
Schneider B, Nagel S, Kaufmann M, Winkelmann S, Bode J, Drexler H, et al.
Leukemia
. 2007 Nov;
22(6):1262-6.
PMID: 17989715
No abstract available.
10.
Nagel S, Leich E, Quentmeier H, Meyer C, Kaufmann M, Drexler H, et al.
Leukemia
. 2007 Nov;
22(2):387-92.
PMID: 17989712
Recurrent chromosomal aberrations in hematopoietic tumors target genes involved in pathogenesis. Their identification and functional characterization are therefore important for the establishment of rational therapies. Here, we investigated genomic amplification...