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R A Buchanan

Explore the profile of R A Buchanan including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 511
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Recent Articles
1.
Wilcox J, Consoli D, Tienda A, Dixit S, Buchanan R, May J, et al.
Neurobiol Dis . 2021 Aug; 158:105486. PMID: 34450329
Non-convulsive epileptiform activity is a common and under-studied comorbidity of Alzheimer's disease that may significantly contribute to onset of clinical symptoms independently of other neuropathological features such as β-amyloid deposition....
2.
Perkins B, Dholasania A, Buchanan R, Bril V
Diabet Med . 2010 Oct; 27(11):1271-9. PMID: 20950385
Aims: Randomized clinical trials have frequently shown improvement in diabetic sensorimotor polyneuropathy in placebo-treated participants, counter to the prevailing concept that it deteriorates with time. We aimed to determine the...
3.
Bril V, Tomioka S, Buchanan R, Perkins B
Diabet Med . 2009 Mar; 26(3):240-6. PMID: 19317818
Introduction: A reliable and valid clinical tool to capture symptoms and signs of diabetic sensorimotor polyneuropathy (DSP) for use in clinical research trials is urgently needed. The validated Toronto Clinical...
4.
Good C, Bay K, Buchanan R, McKeon K, Skinner R, Garcia-Rill E
Neurotoxicol Teratol . 2006 Feb; 28(2):210-9. PMID: 16469482
Prenatal exposure to cigarette smoke is known to produce lasting arousal, attentional and cognitive deficits in humans. The pedunculopontine nucleus (PPN), as the cholinergic arm of the reticular activating system...
5.
Morrison M, Buchanan R, Leon R, Liu C, Green B, Liaw P, et al.
J Biomed Mater Res A . 2005 Jul; 74(3):430-8. PMID: 16013063
Bulk metallic glasses (BMGs) represent an emerging class of materials with an amorphous structure and a unique combination of properties. The objectives of this investigation were to define the electrochemical...
6.
Kochak G, Page J, Buchanan R, Peters R, PADGETT C
J Clin Pharmacol . 1998 Apr; 38(2):166-71. PMID: 9549648
A 56-day pharmacokinetic study of zonisamide was conducted in 24 healthy volunteers. Steady state was achieved in 29 days including two dose escalations, and in an average of 15 days...
7.
Pivovarova N, Leapman R, Buchanan R, Reese T, Andrews S
J Neurosci . 1997 Nov; 17(22):8729-38. PMID: 9348342
Synaptic activity-dependent changes in the spatio-temporal distribution of calcium ions regulate important neuronal functions such as dendritic integration and synaptic plasticity, but the processes that terminate the free Ca2+ transients...
8.
Andrews S, Buchanan R, Leapman R
Scanning Microsc Suppl . 1994 Jan; 8:13-23; discussion 23-4. PMID: 7638482
The availability of a cryotransfer stage, highly efficient electron energy loss spectrometers, and ultra-thin-window energy-dispersive x-ray spectrometers for the VG Microscopes HB501 field-emission scanning transmission electron microscope (STEM) provides this...
9.
Buchanan R, Leapman R, Oconnell M, Reese T, Andrews S
J Struct Biol . 1993 May; 110(3):244-55. PMID: 8373705
Freeze-dried, ultrathin cryosections of directly frozen mouse liver and brain have been prepared and characterized by low-dose dark-field scanning transmission electron microscopy (STEM). These improved cryosections gave images comparable to...
10.
Leapman R, Hunt J, Buchanan R, Andrews S
Ultramicroscopy . 1993 Feb; 49(1-4):225-34. PMID: 8475601
Electron energy loss spectroscopy (EELS) in the scanning transmission electron microscope provides a high sensitivity for microanalysis of certain important biological elements such as calcium whose physiological concentrations in cells...