Quirin Hammer
Overview
Explore the profile of Quirin Hammer including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1563
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Recent Articles
1.
Bilev E, Wild N, Momayyezi P, Sala B, Sun R, Sandalova T, et al.
PLoS Pathog
. 2024 Dec;
20(12):e1012755.
PMID: 39652590
In addition to adaptive immunity, natural killer (NK) cells of the innate immune system contribute to the control of viral infections. The HLA-E-restricted SARS-CoV-2 Nsp13232-240 epitope VMPLSAPTL renders infected cells...
2.
Strunz B, Momayyezi P, Bilev E, Muvva J, Chen P, Bister J, et al.
Genes Immun
. 2024 Nov;
26(1):70-74.
PMID: 39487235
Host genetics shape immune responses and influence severity of infectious diseases. The HLA-B -21 M/T dimorphism tunes the functionality of natural killer (NK) cells expressing the inhibitory receptor NKG2A. NKG2A...
3.
Saetersmoen M, Kotchetkov I, Torralba-Raga L, Mansilla-Soto J, Sohlberg E, Krokeide S, et al.
Med
. 2024 Oct;
6(2):100521.
PMID: 39423821
Background: Human leukocyte antigen (HLA)-E is overexpressed by a large proportion of solid tumors, including malignant glioblastoma, and acts as a major checkpoint for NKG2A CD8 T cells and natural...
4.
Hammer Q, Perica K, Mbofung R, van Ooijen H, Martin K, Momayyezi P, et al.
Cell Stem Cell
. 2024 Jul;
31(9):1376-1386.e8.
PMID: 38981470
Allogeneic cellular immunotherapies hold promise for broad clinical implementation but face limitations due to potential rejection of donor cells by the host immune system. Silencing of beta-2 microglobulin (B2M) expression...
5.
Martin K, Hammer Q, Perica K, Sadelain M, Malmberg K
Nat Rev Immunol
. 2024 Apr;
24(9):680-693.
PMID: 38658708
Allogeneic cellular immunotherapies hold a great promise for cancer treatment owing to their potential cost-effectiveness, scalability and on-demand availability. However, immune rejection of adoptively transferred allogeneic T and natural killer...
6.
Hammer Q, Perica K, van Ooijen H, Mbofung R, Momayyezi P, Varady E, et al.
bioRxiv
. 2023 Oct;
PMID: 37873468
Allogeneic cell therapies hold promise for broad clinical implementation, but face limitations due to potential rejection by the recipient immune system. Silencing of beta-2-microglobulin ( ) expression is commonly employed...
7.
Momayyezi P, Bilev E, Ljunggren H, Hammer Q
Eur J Immunol
. 2023 Aug;
53(11):e2350465.
PMID: 37526136
Natural killer (NK) cells are innate lymphocytes that participate in immune responses against virus-infected cells and tumors. As a countermeasure, viruses and tumors employ strategies to evade NK-cell-mediated immunosurveillance. In...
8.
Philippon C, Tao S, Clement D, Haroun-Izquierdo A, Kichula K, Netskar H, et al.
Blood Adv
. 2023 Jun;
7(16):4492-4504.
PMID: 37327114
The functionality of natural killer (NK) cells is tuned during education and is associated with remodeling of the lysosomal compartment. We hypothesized that genetic variation in killer cell immunoglobulin-like receptor...
9.
Hammer Q, Cuapio A, Bister J, Bjorkstrom N, Ljunggren H
J Leukoc Biol
. 2023 Mar;
114(5):507-512.
PMID: 36976012
Natural killer cells participate in the host innate immune response to viral infection. Conversely, natural killer cell dysfunction and hyperactivation can contribute to tissue damage and immunopathology. Here, we review...
10.
Momayyezi P, Malmberg K, Hammer Q
Curr Protoc
. 2022 Nov;
2(11):e613.
PMID: 36440989
Studying gene functions in human natural killer (NK) cells is key for advancing the understanding of NK cell biology and holds promise to pave the way for improving NK cell...