Qixian Chen
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Explore the profile of Qixian Chen including associated specialties, affiliations and a list of published articles.
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85
Citations
559
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Recent Articles
1.
Li T, Wang Y, Chen X, Cui H, Zhang L, Liu J, et al.
ACS Nano
. 2025 Mar;
PMID: 40072892
Small interfering RNA (siRNA) has garnered tremendous interest as a potential therapeutic tool because of its intriguing gene-silencing ability. Toward the success in the manufacture of siRNA therapeutics for the...
2.
Zeng S, Chen C, Yu D, Jiang M, Li X, Liu X, et al.
Adv Sci (Weinh)
. 2025 Jan;
12(9):e2409007.
PMID: 39804952
Activating the pyroptosis pathway of tumor cells by photodynamic therapy (PDT) for immunogenic cell death (ICD) is considered a valid strategy in pursuit of antitumor immunotherapy, but it remains a...
3.
Liu H, Ding Y, Huang D, Zhang C, Yuan F, Chen Q, et al.
J Agric Food Chem
. 2024 Dec;
73(1):289-297.
PMID: 39729021
Plant natural products are crucial in defending against herbivorous insects and are widely used in pest control, yet their mechanisms remain complex and insufficiently studied. This study employed a reverse...
4.
Liu J, Li Y, Zhou K, Zhang S, Wang Y, Wang X, et al.
Bioconjug Chem
. 2024 Sep;
35(9):1417-1428.
PMID: 39225485
Electrostatic self-assembly between negatively charged nucleic acids and cationic materials is the basis for the formulation of the delivery systems. Nevertheless, structural disintegration occurs because their colloidal stabilities are frequently...
5.
Wang Y, Liu J, Tong C, Li L, Cui H, Zhang L, et al.
J Nanobiotechnology
. 2024 Jul;
22(1):413.
PMID: 39004736
Peripheral arterial diseases (PAD) have been reported to be the leading cause for limb amputations, and the current therapeutic strategies including antiplatelet medication or intervene surgery are reported to not...
6.
Hao T, Zhang B, Li W, Yang X, Wu S, Yuan Y, et al.
ACS Appl Mater Interfaces
. 2024 Jun;
16(27):34620-34631.
PMID: 38934519
Polyplexes are required to be equipped with multiple functionalities to accomplish adequate structure stability and gene transfection efficacy for gene therapy. Herein, a 4-carboxy-3-fluorophenylboronic acid (FPBA)-functionalized block copolymer of PEG--PAsp(DET/FBA)...
7.
Wang Y, Liu J, Cui H, Zhang L, Li Z, Wang X, et al.
Biomaterials
. 2024 Jun;
311:122677.
PMID: 38917704
The surface physiochemical properties of nanomedicine play a crucial role in modulating biointerfacial reactions in sequential biological compartments, accordingly accomplishing the desired programmed delivery scenario to intracellular targets. PEGylation, which...
8.
Shen Y, Pan Y, Chen Q, Sun Z, Cai W, Jiang Z, et al.
ACS Sens
. 2024 Jun;
9(6):3367-3376.
PMID: 38885468
Instability is a key challenge for current pH sensors in practical applications, especially in aquatic environments with high biomass and redox substances. Herein, we present a novel approach that uses...
9.
Qin C, Wang H, Cui H, Wang Y, Zhang M, Li H, et al.
J Colloid Interface Sci
. 2024 Jun;
672:350-362.
PMID: 38850862
To overcome the biological barriers in the journey of systemic gene delivery, a multifaceted genomic synthetic nanomedicine was elaborated and strategically equipped with a multiple of intriguing responsiveness. Particularly, core-shell...
10.
Li N, Yu Y, Chen Q, Niu J, Gao C, Qu X, et al.
Acta Biomater
. 2024 Jun;
183:278-291.
PMID: 38838905
Anti-angiogenesis has emerged a promising strategy against colorectal cancer (CRC). However, the efficacy of anti-angiogenic therapy is greatly compromised by the up-regulated autophagy levels resulting from the evolutionary resistance mechanism...