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Qiuting Hong

Explore the profile of Qiuting Hong including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 233
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Recent Articles
1.
Maverakis E, Merleev A, Park D, Kailemia M, Xu G, Ruhaak L, et al.
Clin Immunol . 2021 Aug; 230:108825. PMID: 34403816
We have recently introduced multiple reaction monitoring (MRM) mass spectrometry as a novel tool for glycan biomarker research and discovery. Herein, we employ this technique to characterize the site-specific glycan...
2.
Merleev A, Park D, Xie Y, Kailemia M, Xu G, Ruhaak L, et al.
Sci Rep . 2020 Oct; 10(1):17505. PMID: 33060657
Alterations in the human glycome have been associated with cancer and autoimmunity. Thus, constructing a site-specific map of the human glycome for biomarker research and discovery has been a highly...
3.
Linz T, Yeo D, Hong Q, Zmolek W, McFarland J, Barfield R, et al.
Antibodies (Basel) . 2019 Sep; 7(4). PMID: 31544890
We hypothesized that systematic liquid chromatography-tandem mass spectrometry investigations of an antibody-drug conjugate (ADC), its small and large molecular components, and surrogate small-molecule conjugates might comprise a simple and efficient...
4.
Miyamoto S, Stroble C, Taylor S, Hong Q, Lebrilla C, Leiserowitz G, et al.
J Proteome Res . 2017 Dec; 17(1):222-233. PMID: 29207246
Protein glycosylation fingerprints are widely recognized as potential markers for disease states, and indeed differential glycosylation has been identified in multiple types of autoimmune diseases and several types of cancer....
5.
Tsai T, Hao Z, Hong Q, Moore B, Stella C, Zhang J, et al.
Sci Rep . 2017 Aug; 7(1):7896. PMID: 28801661
Peptide mapping with liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an important analytical method for characterization of post-translational and chemical modifications in therapeutic proteins. Despite its importance, there is currently no...
6.
Huang J, Kailemia M, Goonatilleke E, Parker E, Hong Q, Sabia R, et al.
Anal Bioanal Chem . 2016 Nov; 409(2):589-606. PMID: 27796459
Human milk plays a substantial role in the child growth, development and determines their nutritional and health status. Despite the importance of the proteins and glycoproteins in human milk, very...
7.
Ruhaak L, Kim K, Stroble C, Taylor S, Hong Q, Miyamoto S, et al.
J Proteome Res . 2016 Jan; 15(3):1002-10. PMID: 26813784
Previous studies indicated that glycans in serum may serve as biomarkers for diagnosis of ovarian cancer; however, it was unclear to which proteins these glycans belong. We hypothesize that protein-specific...
8.
Hong Q, Ruhaak L, Stroble C, Parker E, Huang J, Maverakis E, et al.
J Proteome Res . 2015 Oct; 14(12):5179-92. PMID: 26510530
A comprehensive glycan map was constructed for the top eight abundant glycoproteins in plasma using both specific and nonspecific enzyme digestions followed by nano liquid chromatography (LC)-chip/quadrupole time-of-flight mass spectrometry...
9.
Hong Q, Ruhaak L, Totten S, Smilowitz J, German J, Lebrilla C
Anal Chem . 2014 Feb; 86(5):2640-7. PMID: 24502421
An absolute quantitation method for measuring free human milk oligosaccharides (HMOs) in milk samples was developed using multiple reaction monitoring (MRM). To obtain the best sensitivity, the instrument conditions were...
10.
Hong Q, Lebrilla C, Miyamoto S, Ruhaak L
Anal Chem . 2013 Aug; 85(18):8585-93. PMID: 23944609
Studies aimed toward glycan biomarker discovery have focused on glycan characterization by the global profiling of released glycans. Site-specific glycosylation analysis is less developed but may provide new types of...