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Qiu-Min Lu

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Articles 27
Citations 106
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Recent Articles
1.
Michira B, Wang Y, Mwangi J, Wang K, Asmamaw D, Tadese D, et al.
Microorganisms . 2025 Jan; 12(12. PMID: 39770850
The venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in immunocompromised patients....
2.
Cha L, Yang J, Gao J, Lu X, Chang X, Thuku R, et al.
Zool Res . 2024 Aug; 45(5):1001-1012. PMID: 39147715
Thrombosis and inflammation are primary contributors to the onset and progression of ischemic stroke. The contact-kinin pathway, initiated by plasma kallikrein (PK) and activated factor XII (FXIIa), functions bidirectionally with...
3.
Zhang L, Zhou S, Huang X, Chen Y, Mwangi J, Fang Y, et al.
Int J Mol Sci . 2024 May; 25(10). PMID: 38791374
() is a pathogenic fungus that can cause life-threatening meningitis, particularly in individuals with compromised immune systems. The current standard treatment involves the combination of amphotericin B and azole drugs,...
4.
Zhang L, Yang M, Zhou S, Zhang H, Feng Y, Shi L, et al.
Microbiol Spectr . 2023 May; 11(3):e0308922. PMID: 37140456
Drug resistance against bacteria and fungi has become common in recent years, and it is urgent to discover novel antimicrobial peptides to manage this problem. Many antimicrobial peptides from insects...
5.
Xu K, Zhou M, Wu F, Tang X, Lu Q, Lai R, et al.
Chin J Nat Med . 2021 Jul; 19(7):540-544. PMID: 34247778
A large number of protease inhibitors have been found from leeches, which are essential in various physiological and biological processes. In the curret study, a novel elastase inhibitor was purified...
6.
Ma H, Xiao-Peng T, Yang S, Lu Q, Lai R
Chin J Nat Med . 2016 Sep; 14(8):607-14. PMID: 27608950
It is hypothesized that protease inhibitors play an essential role in survival of venomous animals through protecting peptide/protein toxins from degradation by proteases in their prey or predators. However, the...
7.
Wang Y, Tan J, Du C, Luan N, Yan X, Lai R, et al.
Nat Prod Bioprospect . 2015 Sep; 5(4):209-14. PMID: 26329591
Various bio-active substances in amphibian skins play important roles in survival of the amphibians. Many protease inhibitor peptides have been identified from amphibian skins, which are supposed to negatively modulate...
8.
Jiang W, Hakim M, Luo L, Li B, Yang S, Song Y, et al.
Dongwuxue Yanjiu . 2015 May; 36(3):174-7. PMID: 26018861
As a group of intestinal hormones and neurotransmitters, cholecystokinins (CCKs) regulate and affect pancreatic enzyme secretion, gastrointestinal motility, pain hypersensitivity, digestion and satiety, and generally contain a DYMGWMDFG sequence at...
9.
Chen Z, Wu J, Zhang Y, Yu G, Lee W, Lu Q, et al.
Toxicon . 2010 Nov; 57(1):109-16. PMID: 21040740
Serious clinical symptoms of Trimeresurus jerdonii bite are mainly caused by abnormalities of blood system. We have previously identified and characterized several bioactive components affecting human blood system, such as...
10.
Lu Q, Lai R, Zhang Y
Dongwuxue Yanjiu . 2010 May; 31(1):2-16. PMID: 20446448
Many animals produced a diversity of venoms and secretions to adapt the changes of environments through the long history of evolution. The components including a large quantity of specific and...