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Qiu-Cheng Chen

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Articles 12
Citations 38
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Recent Articles
1.
Chen Q, Kress S, Molinelli R, Wuttig A
Nat Catal . 2024 Mar; 7(2):120-131. PMID: 38434422
Construction of C‒C bonds in medicinal chemistry frequently draws on the reductive coupling of organic halides with ketones or aldehydes. Catalytic C(sp)‒C(sp) bond formation, however, is constrained by the competitive...
2.
Chen Q, Fridman N, Tumanskii B, Gross Z
Chem Sci . 2021 Oct; 12(37):12445-12450. PMID: 34603675
Type III dicopper centres are the heart of the reactive sites of enzymes that catalyze the oxidation of catechols. Numerous synthetic model complexes have been prepared to uncover the fundamental...
3.
Soll M, Chen Q, Zhitomirsky B, Lim P, Termini J, Gray H, et al.
Cell Death Discov . 2020 Aug; 6:67. PMID: 32793397
Development of novel therapeutic strategies to eradicate malignant tumors is of paramount importance in cancer research. In a recent study, we have introduced a facile protocol for the preparation of...
4.
Zhan X, Kolanu S, Fite S, Chen Q, Lee W, Churchill D, et al.
Photochem Photobiol Sci . 2020 Jul; 19(8):996-1000. PMID: 32662800
Toluene, p-xylene and mesitylene were cleanly converted to their corresponding monoaldehydes via mild photooxygenation utilizing transition metal and main group β-CF-substituted corroles. Aldehyde yield increased as more electron-donating CH groups...
5.
Chen Q, Fridman N, Diskin-Posner Y, Gross Z
Chemistry . 2020 Jun; 26(43):9481-9485. PMID: 32491230
Palladium complexes of corrole and sapphyrin were prepared in high yield and fully characterized. The corrole provides a tetradentate/trianionic square planar coordination sphere for Pd , charge balanced by pyridinium....
6.
Zhan X, Yadav P, Diskin-Posner Y, Fridman N, Sundararajan M, Ullah Z, et al.
Dalton Trans . 2019 Jul; 48(32):12279-12286. PMID: 31342035
Tris- and tetrakis-β-trifluoromethylated gallium (3CF-Ga, 4CF-Ga) and aluminum (3CF-Al, 4CF-Al) corrole systems were synthesized by a facile "one-pot" approach from the respective tri- and tetra-iodo starting compounds using the FSOCFCOMe...
7.
Chen Q, Xiao Z, Fite S, Mizrahi A, Fridman N, Zhan X, et al.
Chemistry . 2019 Jun; 25(48):11383-11388. PMID: 31251414
Although the affinity of metallocorroles to axial ligands is quite low, this is not the case when the chelated element is phosphorus. This work is hence focused on the mechanism...
8.
Zhan X, Teplitzky P, Diskin-Posner Y, Sundararajan M, Ullah Z, Chen Q, et al.
Inorg Chem . 2019 Apr; 58(9):6184-6198. PMID: 31002247
An eight-member series of CF-substituted difluorophosphorus corroles was prepared for establishing a structure-activity profile of these high-potential photosensitizers. It consisted of preparing all four possible isomers of the monosubstituted corrole...
9.
Soll M, Goswami T, Chen Q, Saltsman I, Teo R, Shahgholi M, et al.
Sci Rep . 2019 Feb; 9(1):2294. PMID: 30783138
Recent work has highlighted the potential of metallocorroles as versatile platforms for the development of drugs and imaging agents, since the bioavailability, physicochemical properties and therapeutic activity can be dramatically...
10.
Chen Q, Saltsman I, Kaushansky A, Xiao Z, Fridman N, Zhan X, et al.
Chemistry . 2018 Aug; 24(65):17255-17261. PMID: 30138537
Rhodium insertion into the new 5,10,15,20-tetrakis(trifluoromethyl)sapphyrin was found to be much more facile than for other analogues, owing to NH⋅⋅⋅F hydrogen-bonding interactions that stabilise the pyrrole-inverted structure characteristic of the...