Qingyan Ruan
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Explore the profile of Qingyan Ruan including associated specialties, affiliations and a list of published articles.
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5
Citations
42
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Recent Articles
1.
Wu M, Li H, Sun X, Zhong R, Cai L, Chen R, et al.
JCI Insight
. 2025 Jan;
10(5).
PMID: 39883525
Renal osteodystrophy is commonly seen in patients with chronic kidney disease (CKD) due to disrupted mineral homeostasis. Given the impaired renal function in these patients, common antiresorptive agents, including bisphosphonates,...
2.
Chen R, Cheng T, Xie S, Sun X, Chen M, Zhao S, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(38):e2402332.
PMID: 39049685
Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are common hematological malignancies in adults. Despite considerable research advances, the development of standard therapies, supportive care, and prognosis for the...
3.
Wang J, Li Y, Yang Y, Xiao C, Ruan Q, Li P, et al.
Int J Biol Macromol
. 2023 May;
242(Pt 3):124910.
PMID: 37217041
Ophiorrhiza pumila, as a folk herb belonging to the Rubiaceae family, has become a potential source of camptothecin (CPT), which is a monoterpenoid indole alkaloid with good antitumor property. However,...
4.
Hao X, Wang C, Zhou W, Ruan Q, Xie C, Yang Y, et al.
J Integr Plant Biol
. 2022 Oct;
65(1):133-149.
PMID: 36194508
Camptothecin (CPT) is an anticancer pentacyclic quinoline alkaloid widely used to treat cancer patients worldwide. However, the biosynthetic pathway and transcriptional regulation of camptothecin are largely unknown. Ophiorrhiza pumila, the...
5.
Ruan Q, Patel G, Wang J, Luo E, Zhou W, Sieniawska E, et al.
Food Chem Toxicol
. 2021 Mar;
151:112113.
PMID: 33722602
Camptothecin (CPT), a well-known monoterpenoid indole alkaloid with broad-spectrum anti-cancer activity, is produced from plants and endophytes. In view of the limitations of plants as sources of camptothecin in productivity...
6.
Hao X, Xie C, Ruan Q, Zhang X, Wu C, Han B, et al.
Hortic Res
. 2021 Jan;
8(1):7.
PMID: 33384421
The limited bioavailability of plant-derived natural products with anticancer activity poses major challenges to the pharmaceutical industry. An example of this is camptothecin, a monoterpene indole alkaloid with potent anticancer...