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Qingchun Zeng

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Articles 87
Citations 1028
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Recent Articles
1.
Wen L, Lin X, Hu D, Li J, Xie K, Li S, et al.
Atherosclerosis . 2025 Feb; 402:119109. PMID: 39952076
Background: Trimethylamine N-oxide (TMAO) is a gut microbial metabolite that promotes calcified aortic valve disease (CAVD), but the underlying mechanism remains obscure. Herein, we aim to test the hypothesis that...
2.
Xian G, Huang R, Hu D, Xu M, Chen Y, Ren H, et al.
Cardiovasc Res . 2025 Feb; PMID: 39913240
Aims: Calcific aortic valve disease (CAVD) has become an increasingly important global medical problem without effective pharmacological intervention. Accumulating evidence indicates that aortic valve calcification is driven by inflammation. Interleukin-1...
3.
Zhang H, Xu T, Mei X, Zhao Q, Yang Q, Zeng X, et al.
Clin Transl Med . 2025 Jan; 15(1):e70166. PMID: 39763059
Introduction: Heart failure with preserved ejection fraction (HFpEF) is a complex condition characterized by metabolic dysfunction and myocardial lipotoxicity. The roles of PTEN-induced kinase 1 (PINK1) and peroxiredoxin-2 (Prdx2) in...
4.
Zhou H, Wang X, Xu T, Gan D, Ma Z, Zhang H, et al.
Cardiovasc Res . 2024 Nov; PMID: 39498806
Aims: Sterile inflammation is implicated in the development of heart failure (HF). Mitochondria plays important roles in triggering and maintaining inflammation. Mitophagy is important for regulation of mitochondrial quality and...
5.
Sherzad A, Zalmai A, Zafarzai I, Zazai M, Zeng Q
Pediatric Health Med Ther . 2024 Oct; 15:299-309. PMID: 39371077
Background: Congenital heart disease (CHD), characterized by anatomical and functional abnormalities of the heart, can impair an individual's quality of life and, if not treated with appropriate interventions, it can...
6.
Xi R, Mumtaz M, Xu D, Zeng Q
Rev Cardiovasc Med . 2024 Oct; 25(9):330. PMID: 39355586
With the escalating incidence of heart failure, accurate diagnosis is paramount for tailored therapeutic interventions. The tricuspid valve, particularly tricuspid regurgitation, once relegated as the "forgotten valve", has gained prominence...
7.
Luo J, Li L, Zeng Q
Int Heart J . 2024 Sep; 65(5):913-928. PMID: 39343595
In addition to its antihypertensive and diuretic effects, hydrochlorothiazide also demonstrates additional cardioprotective properties; however, the existence of a synergistic interaction between dapagliflozin and hydrochlorothiazide remains unclear.To establish a rat...
8.
Zeng X, Zhang H, Xu T, Mei X, Wang X, Yang Q, et al.
Transl Res . 2024 Jul; 273:90-103. PMID: 39059761
Doxorubicin (DOX) is restricted due to its severe cardiotoxicity. There is still a lack of viable and effective drugs to prevent or treat DOX-induced cardiotoxicity(DIC). Vericiguat is widely used to...
9.
Xian G, Huang R, Xu M, Zhao H, Xu X, Chen Y, et al.
Exp Mol Med . 2024 Jun; 56(7):1560-1573. PMID: 38945954
Calcific aortic valve disease (CAVD) is becoming an increasingly important global medical problem, but effective pharmacological treatments are lacking. Noncoding RNAs play a pivotal role in the progression of cardiovascular...
10.
Yang X, Zeng J, Xie K, Su S, Guo Y, Zhang H, et al.
Mol Med . 2024 Jun; 30(1):76. PMID: 38840067
Background: Advanced glycation end product-modified low-density lipoprotein (AGE-LDL) is related to inflammation and the development of atherosclerosis. Additionally, it has been demonstrated that receptor for advanced glycation end products (RAGE)...