Qianting Zhai
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Explore the profile of Qianting Zhai including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
718
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Recent Articles
1.
Zhai Q, He M, Song A, Deshayes K, Dixit V, Carter P
J Mol Biol
. 2016 Jan;
428(3):603-617.
PMID: 26778617
Context-independent anti-hypusine antibodies that bind to the post-translational modification (PTM), hypusine, with minimal dependence on flanking amino acid sequences, were identified. The antibodies bind to both hypusine and deoxyhypusine or...
2.
Spiess C, Zhai Q, Carter P
Mol Immunol
. 2015 Feb;
67(2 Pt A):95-106.
PMID: 25637431
Bispecific antibodies are on the cusp of coming of age as therapeutics more than half a century after they were first described. Two bispecific antibodies, catumaxomab (Removab(®), anti-EpCAM×anti-CD3) and blinatumomab...
3.
Zhai Q, Landesman M, Robinson H, Sundquist W, Hill C
PLoS One
. 2011 Dec;
6(12):e27466.
PMID: 22162750
Background: Bro1 domains are elongated, banana-shaped domains that were first identified in the yeast ESCRT pathway protein, Bro1p. Humans express three Bro1 domain-containing proteins: ALIX, BROX, and HD-PTP, which function...
4.
Zhai Q, Landesman M, Chung H, Dierkers A, Jeffries C, Trewhella J, et al.
J Virol
. 2011 Jul;
85(17):9222-6.
PMID: 21715492
The cellular ALIX protein functions within the ESCRT pathway to facilitate intralumenal endosomal vesicle formation, the abscission stage of cytokinesis, and enveloped virus budding. Here, we report that the C-terminal...
5.
Zhai Q, Landesman M, Robinson H, Sundquist W, Hill C
J Virol
. 2010 Oct;
85(1):632-7.
PMID: 20962096
Retroviral Gag proteins contain short late-domain motifs that recruit cellular ESCRT pathway proteins to facilitate virus budding. ALIX-binding late domains often contain the core consensus sequence YPX(n)L (where X(n) can...
6.
Schubert H, Zhai Q, Sandrin V, Eckert D, Garcia-Maya M, Saul L, et al.
Proc Natl Acad Sci U S A
. 2010 Oct;
107(42):17951-6.
PMID: 20880831
HIV-1 and other enveloped viruses can be restricted by a host cellular protein called BST2/tetherin that prevents release of budded viruses from the cell surface. Mature BST2 contains a small...
7.
Zhai Q, Fisher R, Chung H, Myszka D, Sundquist W, Hill C
Nat Struct Mol Biol
. 2007 Dec;
15(1):43-9.
PMID: 18066081
Retrovirus budding requires short peptide motifs (late domains) located within the viral Gag protein that function by recruiting cellular factors. The YPX(n)L late domains of HIV and other lentiviruses recruit...
8.
Fisher R, Chung H, Zhai Q, Robinson H, Sundquist W, Hill C
Cell
. 2007 Mar;
128(5):841-52.
PMID: 17350572
ALIX/AIP1 functions in enveloped virus budding, endosomal protein sorting, and many other cellular processes. Retroviruses, including HIV-1, SIV, and EIAV, bind and recruit ALIX through YPX(n)L late-domain motifs (X =...