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Qian-Nan Li

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Citations 110
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Recent Articles
1.
Gu L, Li L, Li Q, Xu K, Yue W, Qiao J, et al.
J Genet Genomics . 2024 Apr; 51(8):824-835. PMID: 38657948
Environmental factors such as diet and lifestyle can influence the health of both mothers and offspring. However, its transgenerational transmission and underlying mechanisms remain largely unknown. Here, using a maternal...
2.
Li Q, Hou G, Sun S, Liu W, Meng T, Hou Y, et al.
Aging (Albany NY) . 2023 Jul; 15(13):6292-6301. PMID: 37413994
Heavy drinking in women is known to adversely affect pregnancy and fertility. However, pregnancy is a complex process, and the adverse effects of ethanol on pregnancy does not mean that...
3.
Shang J, Jiao J, Li Q, Lu Y, Wang J, Yan M, et al.
Zhongguo Zhong Yao Za Zhi . 2023 Apr; 48(6):1597-1605. PMID: 37005848
The purpose of this study is to investigate whether chrysin reduces cerebral ischemia-reperfusion injury(CIRI) by inhi-biting ferroptosis in rats. Male SD rats were randomly divided into a sham group, a...
4.
Li Q, Shang J, Jiang T, Bi L, Jiao J, Lu Y, et al.
Zhongguo Zhong Yao Za Zhi . 2022 Sep; 47(15):4110-4118. PMID: 36046901
This study aims to explore the mechanism of "simultaneous treatment of the brain and the heart" of Naoxintong Capsules(NXT) under cerebral ischemia based on Toll-like receptor(TLR) signaling pathway.Male SD rats...
5.
Meng T, Lei W, Lu X, Liu X, Ma X, Nie X, et al.
Int J Biol Sci . 2022 Jul; 18(11):4513-4531. PMID: 35864958
During oocyte growth, various epigenetic modifications are gradually established, accompanied by accumulation of large amounts of mRNAs and proteins. However, little is known about the relationship between epigenetic modifications and...
6.
Dong M, Li Q, Fan L, Li L, Shen W, Wang Z, et al.
Front Cell Dev Biol . 2021 Aug; 9:706879. PMID: 34381787
Aims: Research evidence indicates that epigenetic modifications of gametes in obese or diabetic parents may contribute to metabolic disorders in offspring. In the present study, we sought to address the...
7.
Yuan R, Wang F, Li S, Ma J, Guo L, Li X, et al.
J Assist Reprod Genet . 2021 Apr; 38(6):1373-1385. PMID: 33914207
Insufficiency of oocyte activation impairs the subsequent embryo development in assisted reproductive technology (ART). Intracellular Ca concentration ([Ca]i) oscillations switch the oocytes to resume the second meiosis and initiate embryonic...
8.
Li Q, Li A, Sun S, Liu W, Meng T, Guo X, et al.
Biochem Biophys Res Commun . 2020 Sep; 533(3):586-591. PMID: 32980117
During follicle growth, DNA methylation is gradually established, which is important for oocyte developmental competence. Due to the facts that oocytes from prepubertal individuals show reduced developmental outcomes when compared...
9.
Wang F, Li A, Li Q, Fan L, Wang Z, Meng T, et al.
Cell Biochem Funct . 2020 Jul; 39(2):248-257. PMID: 32643225
Oocyte activation deficiency leads to female infertility. [Ca ] oscillations are required for mitochondrial energy supplement transition from the resting to the excited state, but the underlying mechanisms are still...
10.
Li Q, Ma J, Liu W, Meng T, Wang F, Hou Y, et al.
Mol Reprod Dev . 2020 Jun; 87(7):800-807. PMID: 32558133
The genome methylation is globally erased in early fetal germ cells, and it is gradually re-established during gametogenesis. The expression of some imprinted genes is regulated by the methylation status...