Pushkar P Lele
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Explore the profile of Pushkar P Lele including associated specialties, affiliations and a list of published articles.
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33
Citations
548
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Recent Articles
1.
Wang T, Abolghasemzade S, McKee B, Singh I, Pendyala K, Mohajeri M, et al.
Nat Commun
. 2024 Nov;
15(1):10151.
PMID: 39578439
Extracellular matrix (ECM) stiffness influences cancer cell fate by altering gene expression. Previous studies suggest that stiffness-induced nuclear deformation may regulate gene expression through YAP nuclear localization. We investigated the...
2.
Shanmughan P, Subrahmaniyan P, Bhatnagar D, Ranganathan S, Lele P
Biotechnol Bioeng
. 2024 Nov;
122(2):405-414.
PMID: 39491522
Helicobacter pylori cells undergo chemotaxis toward several small molecules, called chemo-attractants, including urea produced by the epithelial cells of the stomach. The biophysical mechanisms of chemotaxis are not well understood...
3.
Mukhopadhyay S, Bishayi R, Shaji A, Lee A, Gupta R, Mohajeri M, et al.
bioRxiv
. 2024 Mar;
PMID: 38496420
Bacteria can tolerate antibiotics despite lacking the genetic components for resistance. The prevailing notion is that tolerance results from depleted cellular energy or cell dormancy. In contrast to this view,...
4.
Vidwans N, Rhee K, Lele P, Vaddiraju S
ACS ES T Water
. 2024 Jan;
3(9):2938-2947.
PMID: 38204756
The current methods used to study photocatalysis-assisted water disinfection at a laboratory scale may not lead to process scale-up for large-scale implementation. These methods do not capture the process complexity...
5.
Antani J, Shaji A, Gupta R, Lele P
Annu Rev Chem Biomol Eng
. 2023 Dec;
15(1):51-62.
PMID: 38048436
infections are a major cause of peptic ulcers and gastric cancers. The development of robust inflammation in response to these flagellated, motile bacteria is correlated with poor prognosis. Chemotaxis plays...
6.
Lee A, Gupta R, Nguyen H, Schmitz I, Siegele D, Lele P
mBio
. 2023 Jan;
14(1):e0238422.
PMID: 36598258
Bacterial infections that are difficult to eradicate are often treated by sequentially exposing the bacteria to different antibiotics. Although effective, this approach can give rise to epigenetic or other phenomena...
7.
Manson M, Nan B, Lele P, Liu J, Duncan T
Front Microbiol
. 2022 Oct;
13:1012681.
PMID: 36212881
No abstract available.
8.
Gupta R, Yuan J, Lele P
Front Microbiol
. 2022 Jul;
13:928408.
PMID: 35875555
The evolution of the bacterial flagellum gave rise to motility and repurposing of a signaling network, now termed the chemotaxis network, enabled biasing of cell movements. This made it possible...
9.
Gupta R, Rhee K, Beagle S, Chawla R, Perdomo N, Lockless S, et al.
PNAS Nexus
. 2022 Jun;
1(2).
PMID: 35719892
Indole is a major component of the bacterial exometabolome, and the mechanisms for its wide-ranging effects on bacterial physiology are biomedically significant, although they remain poorly understood. Here, we determined...
10.
Katiyar A, Zhang J, Antani J, Yu Y, Scott K, Lele P, et al.
Adv Sci (Weinh)
. 2022 Jun;
9(23):e2201248.
PMID: 35712768
Migrating cells must deform their stiff cell nucleus to move through pores and fibers in tissue. Lamin A/C is known to hinder cell migration by limiting nuclear deformation and passage...