Prosper N Boyaka
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Explore the profile of Prosper N Boyaka including associated specialties, affiliations and a list of published articles.
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63
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1128
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Recent Articles
1.
Zhang Y, Chamblee M, Xu J, Qu P, Shamseldin M, Yoo S, et al.
Nat Commun
. 2024 Jul;
15(1):5589.
PMID: 38961063
As the new SARS-CoV-2 Omicron variants and subvariants emerge, there is an urgency to develop intranasal, broadly protective vaccines. Here, we developed highly efficacious, intranasal trivalent SARS-CoV-2 vaccine candidates (TVC)...
2.
Joldrichsen M, Kim E, Steiner H, Jeong Y, Premanandan C, Hsueh W, et al.
bioRxiv
. 2024 Apr;
PMID: 38617293
Obesity has been associated with dysbiosis, but innate mechanisms linking intestinal epithelial cell subsets and obesity remain poorly understood. Using mice lacking Paneth cells (Sox9 mice), small intestinal epithelial cells...
3.
Xu J, Zhang Y, Qu P, Shamseldin M, Yoo S, Misny J, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(41):e2220403120.
PMID: 37796985
As SARS-CoV-2 variants of concern (VoCs) that evade immunity continue to emerge, next-generation adaptable COVID-19 vaccines which protect the respiratory tract and provide broader, more effective, and durable protection are...
4.
Lu M, Chamblee M, Zhang Y, Ye C, Dravid P, Park J, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(35):e2110105119.
PMID: 35994646
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main target for neutralizing antibodies (NAbs). The S protein trimer is anchored in the virion membrane...
5.
Zhang Y, Lu M, Mahesh K, Kim E, Shamseldin M, Ye C, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(33):e2201616119.
PMID: 35895717
With the rapid increase in SARS-CoV-2 cases in children, a safe and effective vaccine for this population is urgently needed. The MMR (measles/mumps/rubella) vaccine has been one of the safest...
6.
Kim S, Shukla R, Kim E, Cressman S, Yu H, Baek A, et al.
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740248
Anti-CD3-epsilon (CD3e) monoclonal antibodies (mAbs) and CD3e immunotoxins (ITs) are promising targeted therapy options for various T-cell disorders. Despite significant advances in mAb and IT engineering, vascular leakage syndrome (VLS)...
7.
Eltobgy M, Zani A, Kenney A, Estfanous S, Kim E, Badr A, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(21):e2202012119.
PMID: 35588457
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets...
8.
Liepman R, Swink J, Habing G, Boyaka P, Caddey B, Costa M, et al.
Animals (Basel)
. 2022 Apr;
12(8).
PMID: 35454258
Alterations in the gastrointestinal microbiota after antimicrobial therapy in horses can result in loss of colonization resistance and changes in bacterial metabolic function. It is hypothesized that these changes facilitate...
9.
Wellmerling J, Rayner R, Chang S, Kairis E, Kim S, Sharma A, et al.
FASEB J
. 2022 Apr;
36(5):e22270.
PMID: 35412656
Mutations in the CFTR gene lead to cystic fibrosis, a genetic disease associated with chronic infection and inflammation and ultimately respiratory failure. The most common CF-causing mutation is F508del and...
10.
Feleke Haile A, Alonso S, Berhe N, Bekele Atoma T, Boyaka P, Grace D
Front Vet Sci
. 2022 Mar;
9:734896.
PMID: 35280130
O157:H7 is an emerging foodborne pathogen of public health importance. The objectives of this study were to estimate the prevalence and evaluate the antimicrobial susceptibility pattern and multidrug-resistant profile of...