Preethi Mandati
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Explore the profile of Preethi Mandati including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
67
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Recent Articles
1.
Nyavanandi D, Mandati P, Vidiyala N, Parupathi P, Kolimi P, Mamidi H
Pharmaceutics
. 2025 Jan;
17(1).
PMID: 39861666
In recent years, with the increasing patient population, the need for complex and patient-centric medications has increased enormously. Traditional manufacturing techniques such as direct blending, high shear granulation, and dry...
2.
Mandati P, Nyavanandi D, Narala S, Alzahrani A, Vemula S, Repka M
AAPS PharmSciTech
. 2023 Oct;
24(7):203.
PMID: 37783961
The primary focus of the research is to study the role of cocrystal and amorphous solid dispersion approaches for enhancing solubility and preserving the stability of a poorly soluble drug,...
3.
Nyavanandi D, Mandati P, Narala S, Alzahrani A, Kolimi P, Vemula S, et al.
Pharmaceutics
. 2023 Sep;
15(9).
PMID: 37765237
The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach....
4.
Narala S, Komanduri N, Nyavanandi D, Youssef A, Mandati P, Alzahrani A, et al.
J Drug Deliv Sci Technol
. 2023 May;
82.
PMID: 37124158
Aqueous solubility is one of the key parameters for achieving the desired drug concentration in systemic circulation for better therapeutic outcomes. Carbamazepine (CBZ) is practically insoluble in water, is a...
5.
Nyavanandi D, Narala S, Mandati P, Alzahrani A, Kolimi P, Almotairy A, et al.
AAPS PharmSciTech
. 2023 Jan;
24(1):47.
PMID: 36703024
The current research is focused on investigating the suitability of the twin screw melt granulation (TSMG) approach for improving the solubility of a non-steroidal anti-inflammatory (NSAIDs) drug (ibuprofen), by developing...
6.
Narala S, Nyavanandi D, Mandati P, Youssef A, Alzahrani A, Kolimi P, et al.
Int J Pharm X
. 2023 Jan;
5:100156.
PMID: 36636366
This work developed high drug-load pellets for colon targeting in minimal steps by coupling hot-melt extrusion (HME) with a die-surface cutting pelletizer, offering a potential continuous pellet manufacturing process. Ketoprofen...
7.
Mandati P, Dumpa N, Alzahrani A, Nyavanandi D, Narala S, Wang H, et al.
AAPS PharmSciTech
. 2022 Dec;
24(1):13.
PMID: 36477554
The main objective of the current research was to investigate the effect of tablet shapes (heart-shaped and round tablets) and infill densities (50% and 100%) on the drug release profiles...
8.
Nyavanandi D, Mandati P, Narala S, Alzahrani A, Kolimi P, Pradhan A, et al.
Int J Pharm
. 2022 Oct;
628:122283.
PMID: 36244563
The development of amorphous solid dispersions (ASDs) of high-melting-point drug substances using hot-melt extrusion (HME) continues to be challenging because of the limited availability of polymers that are stable at...
9.
Rangaraj N, Sampathi S, Junnuthula V, Kolimi P, Mandati P, Narala S, et al.
Pharmaceutics
. 2022 Sep;
14(9).
PMID: 36145555
Among various drug administration routes, oral drug delivery is preferred and is considered patient-friendly; hence, most of the marketed drugs are available as conventional tablets or capsules. In such cases,...
10.
Alzahrani A, Narala S, Youssef A, Nyavanandi D, Bandari S, Mandati P, et al.
Eur J Pharm Biopharm
. 2022 Jul;
177:211-223.
PMID: 35835328
Fixed-dose combinations (FDCs) achieve optimal goals for treatment with minimal side effects, decreased administration of large number of tablets, thus, greater convenience, and improved patient compliance. However, conventional FDCs do...