Preben B Mortensen
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Explore the profile of Preben B Mortensen including associated specialties, affiliations and a list of published articles.
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164
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7955
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Recent Articles
1.
Montalbano S, Dybdahl Krebs M, Rosengren A, Vaez M, Georgii Hellberg K, Mortensen P, et al.
NPJ Genom Med
. 2024 Dec;
9(1):67.
PMID: 39695155
The NRXN1 locus is a hotspot for non-recurrent copy number variants and exon-disrupting NRXN1 deletions have been associated with increased risk of neurodevelopmental disorders in case-control studies. However, corresponding population-based...
2.
Vaez M, Montalbano S, Waples R, Dybdahl Krebs M, Georgii Hellberg K, Gadin J, et al.
medRxiv
. 2024 Oct;
PMID: 39398991
The impact of rare recurrent copy number variants (rCNVs) and polygenic background attributed to common variants, on the risk of psychiatric disorders is well-established in separate studies. However, it remains...
3.
Mundy J, Hall A, Steinbach J, Albinana C, Agerbo E, Als T, et al.
Psychol Med
. 2024 Oct;
:1-10.
PMID: 39397681
Background: The clinical course of major depressive disorder (MDD) is heterogeneous, and early-onset MDD often has a more severe and complex clinical course. Our goal was to determine whether polygenic...
4.
Breinbjerg A, Jorgensen C, Walters G, Grove J, Als T, Kamperis K, et al.
J Urol
. 2024 Aug;
212(6):851-861.
PMID: 39093873
Purpose: Childhood incontinence is stigmatized and underprioritized, and a basic understanding of its pathogenesis is missing. Our goal was to identify risk-conferring genetic variants in daytime urinary incontinence (DUI). Materials...
5.
Strom N, Verhulst B, Bacanu S, Cheesman R, Purves K, Gedik H, et al.
medRxiv
. 2024 Jul;
PMID: 39006447
The major anxiety disorders (ANX; including generalized anxiety disorder, panic disorder, and phobias) are highly prevalent, often onset early, persist throughout life, and cause substantial global disability. Although distinct in...
6.
Vaez M, Montalbano S, Calle Sanchez X, Georgii Hellberg K, Dehkordi S, Dybdahl Krebs M, et al.
JAMA Psychiatry
. 2024 Jun;
81(10):957-966.
PMID: 38922630
Importance: Recurrent copy number variants (rCNVs) have been associated with increased risk of psychiatric disorders in case-control studies, but their population-level impact is unknown. Objective: To provide unbiased population-based estimates...
7.
Wimberley T, Brikell I, Astrup A, Larsen J, Petersen L, Albinana C, et al.
Psychol Med
. 2024 May;
54(11):2976-2985.
PMID: 38801094
Background: Psychiatric disorders and type 2 diabetes mellitus (T2DM) are heritable, polygenic, and often comorbid conditions, yet knowledge about their potential shared familial risk is lacking. We used family designs...
8.
Strom N, Gerring Z, Galimberti M, Yu D, Halvorsen M, Abdellaoui A, et al.
medRxiv
. 2024 May;
PMID: 38712091
Obsessive-compulsive disorder (OCD) affects ~1% of the population and exhibits a high SNP-heritability, yet previous genome-wide association studies (GWAS) have provided limited information on the genetic etiology and underlying biological...
9.
Papini N, Presseller E, Bulik C, Holde K, Larsen J, Thornton L, et al.
Psychol Med
. 2024 Feb;
54(9):2073-2086.
PMID: 38347808
Background: Although several types of risk factors for anorexia nervosa (AN) have been identified, including birth-related factors, somatic, and psychosocial risk factors, their interplay with genetic susceptibility remains unclear. Genetic...
10.
Vaez M, Montalbano S, Calle Sanchez X, Georgii Hellberg K, Dehkordi S, Dybdahl Krebs M, et al.
medRxiv
. 2023 Oct;
PMID: 37886536
Recurrent copy number variants (rCNVs) are associated with increased risk of neuropsychiatric disorders but their pathogenic population-level impact is unknown. We provide population-based estimates of rCNV-associated risk of neuropsychiatric disorders...