Pravin C Singhal
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Explore the profile of Pravin C Singhal including associated specialties, affiliations and a list of published articles.
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126
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2140
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Recent Articles
1.
Singhal P, Skorecki K
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001508
APOL1 Renal Risk Variants (APOL1RRVs, G1, and G2) are known to be toxic to glomerular podocytes and causally associated with an enhanced prevalence and progression of many different etiologies of...
2.
Kumar V, Kaur P, Ayasolla K, Jha A, Wiqas A, Vashistha H, et al.
Biomolecules
. 2025 Jan;
14(12.
PMID: 39766282
Patients carrying APOL1 risk alleles (G1 and G2) have a higher risk of developing Focal Segmental Glomerulosclerosis (FSGS); we hypothesized that escalated levels of miR193a contribute to kidney injury by...
3.
Bharati J, Kumar M, Kumar N, Malhotra A, Singhal P
Biomolecules
. 2023 Dec;
13(12).
PMID: 38136614
MicroRNAs (miRNAs) are noncoding small RNAs that regulate the protein expression of coding messenger RNAs. They are used as biomarkers to aid in diagnosing, prognosticating, and surveillance of diseases, especially...
4.
Xue R, Wang Y, Geng L, Xiao H, Kumar V, Lan X, et al.
Int J Biol Macromol
. 2023 Dec;
257(Pt 2):128720.
PMID: 38101684
Comprehensive insight into the gender-based gene expression-related omics data in a rodent model of diabetic nephropathy (DN) is scarce. In the present study, the gender-based genes regulating different pathways involved...
5.
Xue R, Xiao H, Kumar V, Lan X, Malhotra A, Singhal P, et al.
Int J Nephrol Renovasc Dis
. 2023 Dec;
16:241-252.
PMID: 38075191
Diabetic nephropathy (DN) is a common complication affecting many diabetic patients, leading to end-stage renal disease. However, its pathogenesis still needs to be fully understood to enhance the effectiveness of...
6.
Bharati J, Chander P, Singhal P
Biomolecules
. 2023 Feb;
13(2).
PMID: 36830635
Glomerular parietal epithelial cells (PECs) have been increasingly recognized to have crucial functions. Lineage tracking in animal models showed the expression of a podocyte phenotype by PECs during normal glomerular...
7.
Goyal R, Singhal P
FEBS J
. 2020 Dec;
288(19):5586-5597.
PMID: 33340240
HIV-associated nephropathy (HIVAN) remains a concern among untreated HIV patients, notably of African descent, as patients can reach end-stage renal disease within 3 years. Two variants (G1 and G2) of...
8.
Aslam R, Hussain A, Cheng K, Kumar V, Malhotra A, Gupta S, et al.
Histol Histopathol
. 2020 Oct;
35(12):1483-1492.
PMID: 33124682
To determine the role of the transplantation of bone marrow-derived mesenchymal stem cells (MSCs) in podocyte renewal, we studied BALB/C mice with or without adriamycin-induced acute kidney injury. MSCs were...
9.
Valsecchi M, Cazzetta V, Oriolo F, Lan X, Piazza R, Saleem M, et al.
Glycoconj J
. 2020 Sep;
37(6):729-744.
PMID: 32915357
Apolipoprotein L1 (APOL1) wild type (G0) plays a role in the metabolism of sphingolipids, glycosphingolipids, sphingomyelin and ceramide, which constitute bioactive components of the lipid rafts (DRM). We asked whether...
10.
Jha A, Saha S, Ayasolla K, Vashistha H, Malhotra A, Skorecki K, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32316697
Apolipoprotein L1 (APOL1)-miR193a axis has been reported to play a role in the maintenance of podocyte homeostasis. In the present study, we analyzed transcription factors relevant to miR193a in human...