Praveen Kumar Issac
Overview
Explore the profile of Praveen Kumar Issac including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
198
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Recent Articles
1.
Neurotoxic effects of chronic exposure to perfluorobutane sulfonate in adult zebrafish (Danio Rerio)
Santhi J, Issac P, Velayutham M, Rajan P, Althaf Hussain S, Rafi Shaik M, et al.
Comp Biochem Physiol C Toxicol Pharmacol
. 2025 Feb;
292:110162.
PMID: 39993586
Per and polyfluoroalkyl substances (PFAS) are synthetic compounds extensively utilized in industrial applications and consumer products. Long-chain PFAS has been linked to negative health impacts, prompting the introduction of shorter-chain...
2.
Santhi J, Issac P, Velayutham M, Althaf Hussain S, Rafi Shaik M, Shaik B, et al.
Comp Biochem Physiol C Toxicol Pharmacol
. 2025 Jan;
289:110122.
PMID: 39788358
Per and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals extensively used in consumer products. Perfluorobutane sulfonate (PFBS), a short-chain PFAS, has been introduced as an alternative to long-chain PFAS, but limited...
3.
Revathi S, Dey N, Thomas A, Thomas A, Issac P, Rafi Shaik M, et al.
Chem Biodivers
. 2024 Nov;
e202402150.
PMID: 39607692
The demand for plant-based nanocarriers and nanodrugs is increasing due to their versatile nature and compatibility. This research focuses on the optimization of Achillea millefolium-infused chitosan (CS) nanocarriers for antibacterial...
4.
Santhi J, Guru A, Rafi Shaik M, Althaf Hussain S, Issac P
Comp Biochem Physiol C Toxicol Pharmacol
. 2024 Nov;
287:110069.
PMID: 39510332
Perfluorobutane sulfonate (PFBS) is a synthetic organic molecule that belongs to the per and polyfluoroalkyl substances family. Due to its unique physicochemical characteristics, PFBS has been extensively used in consumer...
5.
Vijayanand M, Guru A, Rafi Shaik M, Althaf Hussain S, Issac P
J Biochem Mol Toxicol
. 2024 Oct;
38(11):e70027.
PMID: 39467211
HO is a significant reactive oxygen species (ROS) that hinders redox-mediated processes and contributes to oxidative stress and neurodegenerative disorders. Oxidative stress causes impairment of cell macromolecules, which results in...
6.
Janarathanam V, Issac P, Pan I, Kamaraj N, Ansar S, Kumar Y, et al.
Mol Biol Rep
. 2024 Oct;
51(1):1087.
PMID: 39436450
Background: An excessive amount of reactive oxygen species triggers oxidative stress, leading to an imbalance in cellular homeostasis. Antioxidant therapy is an effective tool for lowering the oxidative stress and...
7.
Sri Snehaa C, Issac P, Rajaguru P, Pugalenthi V
3 Biotech
. 2024 Oct;
14(11):266.
PMID: 39411103
Although combination therapy is known for its high efficacy, reduced side effects and drug resistance, toxicity remains a major drawback. Some of the genes are likely to induce hepatotoxicity through...
8.
Jegadheeshwari S, Santhi J, Velayutham M, Issac P, Kesavan M
Int J Biol Macromol
. 2024 Sep;
280(Pt 4):136099.
PMID: 39343269
Hexavalent chromium (Cr (VI)) contamination poses a significant threat to environmental and human health due to its ability to induce oxidative stress. Conventional strategies to counter Cr (VI)-induced oxidative stress,...
9.
Vijayanand M, Issac P, Velayutham M, Rafi Shaik M, Althaf Hussain S, Guru A
Mol Biol Rep
. 2024 Sep;
51(1):990.
PMID: 39287730
Background: Oxidative stress, a condition characterized by excessive production of reactive oxygen species (ROS), can cause significant damage to cellular macromolecules, leading to neurodegeneration. This underscores the need for effective...
10.
Velumani K, John A, Rafi Shaik M, Althaf Hussain S, Guru A, Issac P
3 Biotech
. 2024 Aug;
14(9):205.
PMID: 39170770
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-024-04050-2.