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Prasanna R Kolatkar

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Articles 58
Citations 950
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Recent Articles
1.
Abu Aqel Y, Alnesf A, Aigha I, Islam Z, Kolatkar P, Teo A, et al.
Cell Mol Biol Lett . 2024 Sep; 29(1):120. PMID: 39245718
Glucokinase (GCK), a key enzyme in glucose metabolism, plays a central role in glucose sensing and insulin secretion in pancreatic β-cells, as well as glycogen synthesis in the liver. Mutations...
2.
Sultana A, Geethakumari A, Islam Z, Kolatkar P, Biswas K
Front Bioeng Biotechnol . 2024 Jun; 12:1353479. PMID: 38887615
The need for the early detection of emerging pathogenic viruses and their newer variants has driven the urgent demand for developing point-of-care diagnostic tools. Although nucleic acid-based methods such as...
3.
Olson N, Kolatkar P, Oliveira M, Cheng R, Greve J, McClelland A, et al.
Protein Eng . 2024 Apr; 6(Suppl):1. PMID: 38626270
No abstract available.
4.
Islam Z, Vaikath N, Hmila I, El-Agnaf O, Kolatkar P
Protein Sci . 2023 Dec; 33(2):e4875. PMID: 38105512
Nanobodies are single-domain fragments of antibodies with comparable specificity and affinity to antibodies. They are emerging as versatile tools in biology due to their relatively small size. Here, we report...
5.
Keyan K, Salim S, Gowda S, Abdelrahman D, Amir S, Islam Z, et al.
Cell Death Dis . 2023 Oct; 14(10):692. PMID: 37863914
Transforming growth factor β (TGFβ) pathway is a master regulator of cell proliferation, differentiation, and death. Deregulation of TGFβ signalling is well established in several human diseases including autoimmune disorders...
6.
Islam Z, Diane A, Khattab N, Dehbi M, Thornalley P, Kolatkar P
PLoS One . 2023 Aug; 18(8):e0290340. PMID: 37594932
Metabolic stress involved in several dysregulation disorders such as type 2 diabetes mellitus (T2DM) results in down regulation of several heat shock proteins (HSPs) including DNAJB3. This down regulation of...
7.
Islam Z, Aldous N, Choi S, Schmidt F, Mifsud B, Abdelalim E, et al.
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430529
Cofactor flavin adenine dinucleotide (FAD), a compound with flavin moiety and a derivative of riboflavin (vitamin B), is shown to bind to Sox9 (a key transcription factor in early pancreatic...
8.
Fatima M, Islam Z, Kolatkar P, Al-Shabeeb Akil A
Molecules . 2022 Jul; 27(13). PMID: 35807283
Obesity is a chronic disease with increasing cases among children and adolescents. Melanocortin 4 receptor (MC4R) is a G protein-coupled transporter involved in solute transport, enabling it to maintain cellular...
9.
Shaath H, Vishnubalaji R, Elango R, Kardousha A, Islam Z, Qureshi R, et al.
Semin Cancer Biol . 2022 Jun; 86(Pt 3):325-345. PMID: 35643221
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which comprise the bulk of the genome, is important for understanding virtually every hallmark of cancer. This large group...
10.
Hmila I, Vaikath N, Majbour N, Erskine D, Sudhakaran I, Gupta V, et al.
FEBS J . 2022 Jan; 289(15):4657-4673. PMID: 35090199
Nanobodies (Nbs), the single-domain antigen-binding fragments of dromedary heavy-chain antibodies (HCAb), are excellent candidates as therapeutic and diagnostic tools in synucleinopathies because of their small size, solubility and stability. Here,...