Prakash Chinnaiyan
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Explore the profile of Prakash Chinnaiyan including associated specialties, affiliations and a list of published articles.
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67
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2202
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Recent Articles
1.
Alka K, Oyeniyi J, Mohammad G, Zhao Y, Marcus S, Chinnaiyan P
Cancers (Basel)
. 2025 Jan;
17(1.
PMID: 39796649
Pancreatic cancer is the third leading cause of cancer-related mortality in the United States, with rising incidence and mortality. The receptor for advanced glycation end products (RAGE) and its ligands...
2.
Kesarwani P, Kant S, Zhao Y, Prabhu A, Buelow K, Miller C, et al.
Nat Commun
. 2023 Mar;
14(1):1459.
PMID: 36927729
There has been considerable scientific effort dedicated to understanding the biologic consequence and therapeutic implications of aberrant tryptophan metabolism in brain tumors and neurodegenerative diseases. A majority of this work...
3.
Scott A, Correa L, Edwards D, Sun Y, Ravikumar V, Andren A, et al.
Antioxid Redox Signal
. 2023 Feb;
39(13-15):942-956.
PMID: 36852494
Targeting tumor metabolism may improve the outcomes for patients with glioblastoma (GBM). To further preclinical efforts targeting metabolism in GBM, we tested the hypothesis that brain tumors can be stratified...
4.
Chang S, Liu G, Zhao L, Zheng W, Yan D, Chen P, et al.
Phys Med Biol
. 2022 Dec;
68(1).
PMID: 36546347
. Proton dosimetric uncertainties resulting from the patient's daily setup errors in rotational directions exist even with advanced image-guided radiotherapy techniques. Thus, we developed a new rotational robust optimization SPArc...
5.
Kesarwani P, Kant S, Zhao Y, Miller C, Chinnaiyan P
Cancers (Basel)
. 2022 Nov;
14(22).
PMID: 36428642
Glioblastoma (GBM) represents an aggressive and immune-resistant cancer. Preclinical investigations have identified anti-tumor activity of a ketogenic diet (KD) potentially being used to target GBM's glycolytic phenotype. Since immune cells...
6.
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
Sponagel J, Jones J, Frankfater C, Zhang S, Tung O, Cho K, et al.
Med
. 2022 Sep;
3(11):792-811.e12.
PMID: 36108629
Background: Brain cancer incidence and mortality rates are greater in males. Understanding the molecular mechanisms that underlie those sex differences could improve treatment strategies. Although sex differences in normal metabolism...
7.
Chang S, Liu G, Zhao L, Zheng W, Yan D, Chen P, et al.
Front Oncol
. 2022 Jun;
12:804036.
PMID: 35664795
Purpose: To explore the role of using Pencil Beam Scanning (PBS) proton beam therapy in single lesion brain stereotactic radiosurgery (SRS), we developed and validated a dosimetric in silico model...
8.
Ramasamy B, Jeyadharmarajan J, Chinnaiyan P
Environ Sci Pollut Res Int
. 2021 Mar;
28(29):39637-39647.
PMID: 33763832
This study is on photocatalytic degradation of pharmaceutical residues of atenolol (ATL) and acetaminophen (ACT) present in secondary effluent under visible light irradiation stimulated by Ag doped ZnO (Ag-ZnO) photocatalyst....
9.
Grzywacz V, Quinn T, Wilson T, Reitemeier P, Navin M, Hamstra D, et al.
Pract Radiat Oncol
. 2021 Feb;
11(5):e449-e458.
PMID: 33548544
Purpose: The purpose of this study was to delineate a scoring system to maximize the ethical allocation of proton beam therapy (PBT) and determine what factors are associated with receipt...
10.
Almahariq M, Quinn T, Kesarwani P, Kant S, Miller C, Chinnaiyan P
In Vivo
. 2021 Jan;
35(1):119-129.
PMID: 33402457
Aim: To use inhibition of colony-stimulating factor-1 receptor (CSF-1R) to target tumor-associated macrophages (TAMs) and improve the efficacy of radiotherapy in glioblastoma (GBM). Materials And Methods: The CSF-1R inhibitor BLZ-945...