Prajan Divakar
Overview
Explore the profile of Prajan Divakar including associated specialties, affiliations and a list of published articles.
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24
Citations
828
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Recent Articles
1.
Single Cell Spatial Transcriptomics Reveals Immunotherapy-Driven Bone Marrow Niche Remodeling in AML
Gui G, Bingham M, Herzog J, Wong-Rolle A, Dillon L, Goswami M, et al.
bioRxiv
. 2025 Feb;
PMID: 39975227
Given the successful graft-versus-leukemia cell treatment effect observed with allogeneic hematopoietic stem cell transplant for patients with refractory or relapsed acute myeloid leukemia, immunotherapies have also been investigated in the...
2.
Rojas-Quintero J, Ochsner S, New F, Divakar P, Xi Yang C, Wu T, et al.
Am J Respir Crit Care Med
. 2023 Dec;
PMID: 38064378
Rationale: Within chronic obstructive pulmonary disease (COPD), emphysema is characterized by a significant yet partially understood B cell immune component. Objective: To characterize the transcriptomic signatures from lymphoid follicles (LFs)...
3.
Rojas-Quintero J, Ochsner S, New F, Divakar P, Xi Yang C, Wu T, et al.
Am J Respir Crit Care Med
. 2023 Nov;
209(1):48-58.
PMID: 37934672
Within chronic obstructive pulmonary disease (COPD), emphysema is characterized by a significant yet partially understood B cell immune component. To characterize the transcriptomic signatures from lymphoid follicles (LFs) in ever-smokers...
4.
Martinez-Morilla S, Moutafi M, Fernandez A, Jessel S, Divakar P, Wong P, et al.
Oncoimmunology
. 2023 Oct;
12(1):2260618.
PMID: 37781235
Although immune checkpoint inhibitor (ICI) therapy has dramatically improved outcome for metastatic melanoma patients, many patients do not benefit. Since adverse events may be severe, biomarkers for resistance would be...
5.
Caruso I, Yin K, Divakar P, Wegst U
J Mech Behav Biomed Mater
. 2023 Jun;
144:105897.
PMID: 37343356
Tensile properties of directionally freeze-cast biopolymer scaffolds are rarely reported, even though they are of interest from a fundamental science perspective and critical in applications such as scaffolds for the...
6.
He Y, Kim I, Bian J, Polyzos A, Di Giammartino D, Zhang Y, et al.
J Thorac Oncol
. 2022 Sep;
17(12):1375-1386.
PMID: 36049655
Introduction: The pathogenesis of thymic epithelial tumors remains largely unknown. We previously identified GTF2I L424H as the most frequently recurrent mutation in thymic epithelial tumors. Nevertheless, the precise role of...
7.
Hwang W, Jagadeesh K, Guo J, Hoffman H, Yadollahpour P, Reeves J, et al.
Nat Genet
. 2022 Jul;
54(8):1178-1191.
PMID: 35902743
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we...
8.
Wong-Rolle A, Dong Q, Zhu Y, Divakar P, Hor J, Kedei N, et al.
J Immunother Cancer
. 2022 Jul;
10(7).
PMID: 35793869
Background: The lung intratumor microbiome influences lung cancer tumorigenesis and treatment responses, but detailed data on the extent, location, and effects of microbes within lung tumors are missing, information needed...
9.
Moutafi M, Martinez-Morilla S, Divakar P, Vathiotis I, Gavrielatou N, Aung T, et al.
J Thorac Oncol
. 2022 May;
17(8):991-1001.
PMID: 35490853
Introduction: Despite the clinical efficacy of immune checkpoint inhibitors (ICIs) in NSCLC, only approximately 20% of patients remain disease-free at 5 years. Here, we use digital spatial profiling to find...
10.
Kim J, Ahn S, Deans K, Thompson D, Ferland B, Divakar P, et al.
Front Bioeng Biotechnol
. 2022 Apr;
10:855755.
PMID: 35372313
A main impediment to effective development of new therapeutics for central nervous system disorders, and for the testing of biological hypotheses in the brain, is the ability to rapidly measure...