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Prado Vargas Duarte

Explore the profile of Prado Vargas Duarte including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Filali-Mouncef Y, Leytens A, Vargas Duarte P, Zampieri M, Dengjel J, Reggiori F
Autophagy . 2024 Jul; 20(10):2323-2337. PMID: 38958087
Autophagosome biogenesis is a complex process orchestrated by dynamic interactions between Atg (autophagy-related) proteins and characterized by the turnover of specific cargoes, which can differ over time and depending on...
2.
Vargas Duarte P, Reggiori F
Contact (Thousand Oaks) . 2023 Jul; 6:25152564231183898. PMID: 37465355
Macroautophagy is characterized by the formation of double-membrane vesicles termed autophagosomes. The precursor structure of autophagosomes is a membrane cistern called phagophore, which elongates through a massive acquisition of lipids...
3.
Vargas Duarte P, Hardenberg R, Mari M, Walter S, Reggiori F, Frohlich F, et al.
J Cell Sci . 2022 Mar; 135(8). PMID: 35343566
Lysosomes mediate degradation of macromolecules to their precursors for cellular recycling. Additionally, lysosome-related organelles mediate cell type-specific functions. Chédiak-Higashi syndrome is an autosomal, recessive disease, in which loss of the...
4.
Eising S, Esch B, Walte M, Vargas Duarte P, Walter S, Ungermann C, et al.
J Cell Biol . 2022 Feb; 221(4). PMID: 35175277
The lysosome is the major catabolic organelle in the cell that has been established as a key metabolic signaling center. Mutations in many lysosomal proteins have catastrophic effects and cause...
5.
Gonzalez Montoro A, Vargas Duarte P, Auffarth K, Walter S, Frohlich F, Ungermann C
Mol Biol Cell . 2021 Oct; 32(22):br14. PMID: 34668759
The hexameric HOPS (homotypic fusion and protein sorting) complex is a conserved tethering complex at the lysosome-like vacuole, where it mediates tethering and promotes all fusion events involving this organelle....