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Pradip De

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Articles 65
Citations 1892
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Recent Articles
1.
Sulaiman R, Aske J, Espaillat L, Lin X, Starks D, Dale A, et al.
Am J Cancer Res . 2024 Jul; 14(6):3083-3103. PMID: 39005689
A scientific interrogation-driven approach to the clinical management of cancer patients is based on molecular profiling of the tumor. Empowered by the knowledge of oncogenic drivers and biomarkers, oncologists chart...
2.
Sulaiman R, Dale A, Lin X, Aske J, Gaster K, Starks D, et al.
Int J Mol Sci . 2024 Mar; 25(6). PMID: 38542414
Lymphovascular invasion (LVSI) is defined as the presence of tumor cells within a definite endothelial-lined space (lymphatics or blood vessels) in the organ surrounding invasive carcinoma. The presence of LVI...
3.
Sulaiman R, Koirala N, Aske J, Lin X, Rojas-Espaillat L, Starks D, et al.
Am J Cancer Res . 2024 Mar; 14(2):467-489. PMID: 38455423
In conversation with endometrial tumor cells, the endometrial cancer-associated fibroblasts (CAFs) are the "partners in crime" of uterine neoplasm's highly heterogeneous tumor microenvironment (TME). We designed a laboratory-friendly method to...
4.
Adashek J, Pandya C, Maragakis N, De P, Cohen P, Kato S, et al.
BMC Med . 2024 Feb; 22(1):74. PMID: 38369520
Background: Neuregulin-1 (NRG1) is implicated in both cancer and neurologic diseases such as amyotrophic lateral sclerosis (ALS); however, to date, there has been little cross-field discussion between neurology and oncology...
5.
Sulaiman R, De P, Aske J, Lin X, Dale A, Koirala N, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37446260
The bipartite landscape of tumor cells and stromal cells determines a tumor's response to treatment during disease management. In endometrial cancers (ECs), the mechanistic contribution of PD-L1/L2 and PD-1 signaling...
6.
Sulaiman R, De P, Aske J, Lin X, Dale A, Gaster K, et al.
Biomedicines . 2023 May; 11(5). PMID: 37238998
The management of advanced or recurrent endometrial cancers presents a challenge due to the development of resistance to treatments. The knowledge regarding the role of the tumor microenvironment (TME) in...
7.
Adashek J, Kato S, Nishizaki D, Miyashita H, De P, Lee S, et al.
Cancer Med . 2023 May; 12(12):13155-13166. PMID: 37132280
Background: Lymphocyte activation gene 3 (LAG-3) or CD223 is a transmembrane protein that serves as an immune checkpoint which attenuates T-cell activation. Many clinical trials of LAG-3 inhibitors have had...
8.
Sulaiman R, De P, Aske J, Lin X, Dale A, Gaster K, et al.
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047422
Cancer-associated fibroblasts (CAFs) within a solid tumor can support the progression of cancer. We studied the identification and characterization of patient-derived endometrial CAFs in the context of their clinical relevance...
9.
Sulaiman R, De P, Aske J, Lin X, Dale A, Koirala N, et al.
Biomedicines . 2023 Jan; 11(1). PMID: 36672620
Ovarian cancers rank first in both aggressiveness and dismal prognosis among gynecological neoplasms. The poor outcome is explained by the fact that most patients present with late-stage disease and progress...
10.
Sulaiman R, De P, Aske J, Lin X, Dale A, Vaselaar E, et al.
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230499
The blood of patients with solid tumors contains circulating tumor-associated cells, including epithelial cells originating from the tumor mass, such as circulating tumor cells (CTCs), or phagocytic myeloid cells (differentiated...