Portia A Kreiger
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Explore the profile of Portia A Kreiger including associated specialties, affiliations and a list of published articles.
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42
Citations
662
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Recent Articles
1.
Zhang M, Cron R, Chu N, Nguyen J, Gordon S, Eloseily E, et al.
J Allergy Clin Immunol
. 2024 Oct;
155(3):1015-1026.e5.
PMID: 39423879
Background: Cytokine storm syndromes (CSSs), including hemophagocytic lymphohistiocytosis (HLH), are increasingly recognized as hyperinflammatory states leading to multiorgan failure and death. Familial HLH in infancy results from homozygous genetic defects...
2.
Ng J, Saikali L, Massenburg B, Wu M, Romeo D, Blum J, et al.
Plast Reconstr Surg
. 2024 Oct;
PMID: 39418069
Background: We examined operative and pathologic findings of a large series of dermoid cysts at a high-volume pediatric hospital over 23 years. Methods: A retrospective review was performed of all...
3.
Gallo P, Elliott E, Ford G, Biswas C, Wheaton J, Kim J, et al.
J Leukoc Biol
. 2024 Oct;
PMID: 39390898
Objective: Macrophage activation syndrome (MAS) is characterized by multi-lineage cytopenias, hypercytokinemia, and tissue hemophagocytosis. Transcription factor Nrf2 is a master regulator of redox homeostasis. In this work we aim to...
4.
Chapin C, Diamond T, Perez A, Kreiger P, Loomes K, Behrens E, et al.
Clin Res Hepatol Gastroenterol
. 2024 Jun;
48(7):102407.
PMID: 38936769
Background And Aims: The majority of indeterminate pediatric acute liver failure (PALF) cases are secondary to immune dysregulation, labeled activated T-cell hepatitis (TCHep). We aimed to describe a cohort of...
5.
Rungsiprakarn P, Ryan A, Wong D, Luo M, Kazahaya K, Arkader A, et al.
JCO Precis Oncol
. 2024 Jun;
8:e2300659.
PMID: 38935896
HMGA2::NCOR2 keratin-positive giant cell tumors in children with response to imatinib in an infant.
6.
Warren M, Reed R, Prasad V, Rajaram V, Roberts D, Kreiger P, et al.
Pediatr Dev Pathol
. 2023 May;
26(4):411-422.
PMID: 37165545
Background: Electron microscopy (EM), once an important component in diagnosing pediatric diseases, has experienced a decline in its use. To assess the impact of this, pediatric pathology practices were surveyed...
7.
Burn T, Miot C, Gordon S, Culberson E, Diamond T, Kreiger P, et al.
J Immunol
. 2022 Aug;
209(5):938-949.
PMID: 35948399
RAG1/RAG2 (RAG) endonuclease-mediated assembly of diverse lymphocyte Ag receptor genes by V(D)J recombination is critical for the development and immune function of T and B cells. The RAG1 protein contains...
8.
Xu F, Viaene A, Ruiz J, Schubert J, Wu J, Chen J, et al.
Acta Neuropathol Commun
. 2022 Jul;
10(1):102.
PMID: 35836290
CIC-rearranged sarcomas are newly defined undifferentiated soft tissue tumors with CIC-associated fusions, and dismal prognosis. CIC fusions activate PEA3 family genes, ETV1/4/5, leading to tumorigenesis and progression. We report two...
9.
Diamond T, Burn T, Nishiguchi M, Minichino D, Chase J, Chu N, et al.
PLoS One
. 2022 Jun;
17(6):e0269553.
PMID: 35671274
Interferon gamma (IFN-γ) is the main cytokine driving organ dysfunction in Familial Hemophagocytic Lymphohistiocytosis (FHL). Blockade of IFN-γ pathway ameliorates FHL hepatitis, both in animal models and in humans with...
10.
Chapin C, Taylor S, Malladi P, Neighbors K, Melin-Aldana H, Kreiger P, et al.
Hepatol Commun
. 2021 Aug;
5(8):1373-1384.
PMID: 34430782
Many patients with indeterminate pediatric acute liver failure (PALF) have evidence of T-cell driven immune injury; however, the precise inflammatory pathways are not well defined. We have characterized the hepatic...