Polina Sysa-Shah
Overview
Explore the profile of Polina Sysa-Shah including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1304
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Recent Articles
1.
Crilly N, Zita M, Beaver A, Sysa-Shah P, Bhalodia A, Gabrielson K, et al.
Microbiol Spectr
. 2025 Jan;
13(2):e0162324.
PMID: 39791886
Importance: African trypanosomiasis is a neglected tropical disease affecting both people and cattle, which represents a major public health problem in sub-Saharan Africa with an enormous socioeconomic impact. Cardiac disease...
2.
Graham M, Wang R, Chikarmane R, Abel B, Vaghasia A, Gupta A, et al.
Nat Commun
. 2024 Aug;
15(1):7414.
PMID: 39198404
How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study...
3.
Fortini F, Vieceli Dalla Sega F, Lazzarini E, Aquila G, Sysa-Shah P, Bertero E, et al.
Biofactors
. 2024 Jul;
51(1):e2091.
PMID: 38994725
Although the epidermal growth factor receptor 2 (ErbB2) and Notch1 signaling pathways have both significant roles in regulating cardiac biology, their interplay in the heart remains poorly investigated. Here, we...
4.
Graham M, Wang R, Chikarmane R, Wodu B, Vaghasia A, Gupta A, et al.
bioRxiv
. 2023 Oct;
PMID: 37905029
The tissue microenvironment in prostate cancer is profoundly altered. While such alterations have been implicated in driving prostate cancer initiation and progression to aggressive disease, how prostate cancer cells and...
5.
Crilly N, Zita M, Beaver A, Sysa-Shah P, Bhalodia A, Gabrielson K, et al.
bioRxiv
. 2023 Oct;
PMID: 37873308
is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been...
6.
Ito T, Saeki H, Guo X, Sysa-Shah P, Tamashiro K, Lee R, et al.
Am J Physiol Regul Integr Comp Physiol
. 2022 Apr;
323(1):R68-R80.
PMID: 35411811
Children born to women who experience stress during pregnancy have an increased risk of atherosclerosis in later life, but few animal models have explored mechanisms. To study this phenomenon, timed-bred...
7.
Ishiyama S, Kissel C, Guo X, Howard A, Saeki H, Ito T, et al.
J Vis Exp
. 2021 May;
(171).
PMID: 33999035
The most recent advance in the treatment of osteosarcoma (OS) occurred in the 1980s when multi-agent chemotherapy was shown to improve overall survival compared to surgery alone. To address this...
8.
Mahmud F, Du Y, Greif E, Boucher T, Dannals R, Mathews W, et al.
J Neuroinflammation
. 2020 Nov;
17(1):344.
PMID: 33203437
An amendment to this paper has been published and can be accessed via the original article.
9.
Mahmud F, Du Y, Greif E, Boucher T, Dannals R, Mathews W, et al.
J Neuroinflammation
. 2020 Sep;
17(1):273.
PMID: 32943056
Background: Osteopontin (OPN) as a secreted signaling protein is dramatically induced in response to cellular injury and neurodegeneration. Microglial inflammatory responses in the brain are tightly associated with the neuropathologic...
10.
Ito T, Saeki H, Guo X, Sysa-Shah P, Coulter J, Tamashiro K, et al.
Carcinogenesis
. 2020 Apr;
41(12):1713-1723.
PMID: 32249286
Children born to women who experience stress during pregnancy have an increased risk of cancer in later life, but no previous animal studies have tested such a link. We questioned...