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Po-Shen Ko

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Articles 34
Citations 135
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Recent Articles
1.
Liu Y, Lin T, Fan N, Ko P, Wang H, Tsai C, et al.
J Microbiol Immunol Infect . 2024 Dec; PMID: 39627110
Background: In recent years, haploidentical hematopoietic stem cell transplantation (haploHSCT) with post-transplant cyclophosphamide (PTCy) has become increasingly prevalent. However, the precise impact of invasive fungal disease (IFD) in relation to...
2.
Wang C, Lin S, Chang K, Cheong H, Wu S, Lee C, et al.
Heliyon . 2024 Nov; 10(21):e39731. PMID: 39568858
Acute myeloid leukemia (AML) establishes an immunosuppressive microenvironment that favors leukemic proliferation. The immune-suppressive cytokines altered antigen processing, and presentation collectively assist AML cells in escaping cytotoxic T-cell surveillance. These...
3.
Chang K, Shiau L, Lin S, Cheong H, Wang C, Ma C, et al.
Mol Med . 2024 Nov; 30(1):196. PMID: 39497033
N6-methyladenosine (m6A) RNA modification orchestrates cellular epitranscriptome through tuning the homeostasis of transcript stability, translation efficiency, and the transcript affinity toward RNA-binding proteins (RBPs). An aberrant m6A deposition on RNA...
4.
Yang T, Tsai C, Wang H, Ko P, Chien S, Lin T, et al.
Ann Hematol . 2024 Sep; 103(11):4661-4670. PMID: 39223286
Hematopoietic stem cell transplantation (HSCT) is pivotal in treating hematologic disorders, yet it poses the risk of post-transplantation pancytopenia. Prophylactic platelet transfusions are often administered to mitigate this risk. Utilizing...
5.
Hsu T, Tsai C, Liu C, Yeh C, Lin F, Hsiao L, et al.
Ann Hematol . 2024 Mar; 103(8):2893-2904. PMID: 38472362
Multiple myeloma (MM) stands as the second most prevalent hematological malignancy, constituting approximately 10% of all hematological malignancies. Current guidelines recommend upfront autologous stem cell transplantation (ASCT) for transplant-eligible MM...
6.
Wang H, Yang F, Yang C, Liu Y, Ko P, Li C, et al.
Exp Hematol Oncol . 2023 Apr; 12(1):35. PMID: 37029450
Introduction: Circulating monocytic myeloid-derived suppressive cells (M-MDSCs) are implicated as a poor prognostic factor and cause CAR T-cell failure in diffuse large B-cell lymphoma (DLBCL). Triggering receptors expressed on myeloid...
7.
Hsu T, Tsai C, Liu C, Yeh C, Lin F, Hsiao L, et al.
Transfus Med Hemother . 2023 Feb; 50(1):39-50. PMID: 36818774
Introduction: Autologous hematopoietic stem cell transplantation (ASCT) is a well-established treatment for patients with multiple myeloma (MM), and adequate stem cell collection must be assured before ASCT. However, prediction of...
8.
Kim W, Fukuhara N, Yoon D, Yamamoto K, Uchida T, Negoro E, et al.
Blood Adv . 2023 Jan; 7(17):4903-4912. PMID: 36661315
Darinaparsin is a novel organic arsenical compound of dimethylated arsenic conjugated to glutathione, with antitumor activity and a mechanism of action markedly different from other available agents. This phase 2,...
9.
Wang H, Yang C, Lin C, Hsiao L, Ko P, Liu Y, et al.
Cancer Med . 2023 Jan; 12(7):8089-8101. PMID: 36647765
Background: Frontline intensification (including consolidative whole-brain radiotherapy or high-dose chemotherapy with autologous stem-cell transplantation after induction therapy) has been proposed to treat primary central nervous system lymphoma (PCNSL). However, no...
10.
Jiang J, Liu C, Yeh C, Yang C, Liu Y, Wang H, et al.
Hematol Oncol . 2022 Oct; 41(1):167-177. PMID: 36305496
Hemophagocytic lymphohistiocytosis (HLH) is a heterogeneous group of hyperinflammatory statuses that are difficult to diagnose and can be life-threatening. Bone marrow (BM) hemophagocytosis is one of the diagnostic criteria according...