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Po-Ku Chen

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Articles 45
Citations 311
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Recent Articles
1.
Chen P, Wey S, Chen D
Expert Rev Clin Immunol . 2025 Feb; :1-12. PMID: 39925174
Introduction: Accumulative evidence indicates that both innate and adaptive immunity are involved in pathogenesis of Still's disease, an autoinflammatory disease. With Increasing insights into the pathogenesis of Still's disease coupled...
2.
Chen P, Chen Y, Chen J, Chen D
Rheumatology (Oxford) . 2024 Oct; PMID: 39447044
Objectives: To maximize the cost-effectiveness of tofacitinib, one of Janus kinase inhibitors, there is an unmet need to identify predictors of therapeutic response. Utilizing phage immunoprecipitation sequencing (PhIP-Seq), we aim...
3.
Chang C, Li Y, Chen P, Chang S, Chen D
Front Cardiovasc Med . 2024 Sep; 11:1449219. PMID: 39323754
Objective: The risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) remains inadequately defined. Consequently, this study aims to evaluate the predictive value of remnant cholesterol (RC) for...
4.
Chen P, Chang S, Chen Y, Chen H, Huang P, Huang C, et al.
Clin Rheumatol . 2024 Jul; 43(8):2503-2511. PMID: 38954278
Herpes zoster (HZ) risk is increased in rheumatoid arthritis (RA) patients receiving Janus kinase inhibitors (JAKi) therapy. Identifying and evaluating the risk factors of HZ development in patients receiving JAKi...
5.
Chen P, Chen Y, Chen H, Liao T, Chang S, Yeo K, et al.
Microorganisms . 2024 May; 12(5). PMID: 38792802
Anti-interferon (IFN)-γ autoantibodies are linked to varicella zoster virus (VZV) infection. Given the elevated risks of herpes zoster (HZ) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis),...
6.
Chen P, Hsu W, Peng C, Liao T, Chang S, Chen H, et al.
Front Med (Lausanne) . 2024 Feb; 11:1347268. PMID: 38371515
Background: Non-alcoholic fatty liver disease (NAFLD) is prevalent among rheumatoid arthritis (RA) patients, but its pathogenesis has rarely been explored. Galectin-9 (Gal-9) interacts with T cell immunoglobulin and mucin-containing-molecule-3 (TIM-3)...
7.
Ho W, Chen H, Chen P, Liao T, Chang S, Chen Y, et al.
BMJ Open . 2024 Jan; 14(1):e079296. PMID: 38272552
Background: Although the non-alcoholic fatty liver disease (NAFLD) is prevalent in the general population, NAFLD risk in newly diagnosed rheumatoid arthritis (RA) has rarely been explored. In this population-based cohort,...
8.
Chen P, Tang K, Chen D
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203796
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by chronic synovitis and the progressive destruction of cartilage and bone. RA is commonly accompanied by extra-articular comorbidities. The pathogenesis of...
9.
Lin Y, Chang S, Hsu T, Chen P, Lan J, Chen D
Clin Exp Rheumatol . 2023 Jul; 41(10):2062-2070. PMID: 37470238
Objectives: Monocyte distribution width (MDW) correlates with volume modifications of circulating monocytes upon activation. Given the crucial role of monocyte activation in the pathogenesis of adult-onset Still's disease (AOSD), we...
10.
Chang C, Chiang E, Chang K, Tang K, Chen P, Yip H, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37445823
Rheumatoid arthritis (RA), a chronic inflammatory disease, carries a significant burden of atherosclerotic cardiovascular diseases (ASCVD). With their heterogeneous composition, high-density lipoprotein (HDL) particles have varied athero-protective properties, and some...