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Piotr Luchowski

Explore the profile of Piotr Luchowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 242
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Recent Articles
21.
Luchowski P, Mitosek-Szewczyk K, Bartosik-Psujek H, Rubaj A, Jankiewicz M, Wojczal J, et al.
Clin Neurol Neurosurg . 2009 Jul; 111(8):676-8. PMID: 19632767
The aim of this study was to evaluate the plasma level changes of B-type natriuretic peptide (BNP), biochemical marker of heart failure, and echocardiographic parameters during mitoxantrone treatment in 22...
22.
Luchowski P, Urbanska E
Eur J Pharmacol . 2007 Mar; 563(1-3):130-3. PMID: 17391664
The influence of nitric oxide (NO) donors, S-nitroso-N-acetylpenicillamine (SNAP), and 3-morpholinosydnonimine (SIN-1), on the central production of an endogenous glutamate receptor antagonist, kynurenic acid, was evaluated in vitro. In cortical...
23.
Urbanska E, Luchowski P, Luchowska E, Pniewski J, Wozniak R, Chodakowska-Zebrowska M, et al.
Pharmacol Rep . 2006 Sep; 58(4):507-11. PMID: 16963796
KYNA, an antagonist of ionotropic glutamate receptors and alpha7 nicotinic receptors, has been found as well in the brain as in the periphery. The altered metabolism of KYNA, especially its...
24.
Stazka J, Luchowski P, Urbanska E
Eur J Pharmacol . 2005 Jun; 517(3):217-23. PMID: 15961072
Increased serum level of homocysteine is an independent risk factor for vascular disease. The effect of DL-homocysteine on the endothelial production of kynurenic acid, an antagonist of alpha7-nicotinic and N-methyl-D-aspartate...
25.
Luchowska E, Luchowski P, Sarnowska A, Wielosz M, Turski W, Urbanska E
Pol J Pharmacol . 2003 Sep; 55(3):443-7. PMID: 14506324
The accumulated data indicate that massively released excitatory amino acids play a major role in mediating the acute ischemic neuronal degeneration. Kynurenic acid (KYNA), the endogenous glutamate receptor antagonist, displaying...
26.
Luchowska E, Luchowski P, Wielosz M, Turski W, Urbanska E
Acta Neurobiol Exp (Wars) . 2003 Aug; 63(2):101-8. PMID: 12926536
Kynurenic acid (KYNA), the only known endogenous glutamate antagonist, is produced in the brain by kynurenine aminotransferases (KATs) I and II. Mitochondrial toxins, 1-methyl-4-phenylpyridinium (MPP +) and 3-nitropropionic acid (3-NPA),...
27.
Kocki T, Luchowski P, Luchowska E, Wielosz M, Turski W, Urbanska E
Neurosci Lett . 2003 Jul; 346(1-2):97-100. PMID: 12850557
In the present study the effect of endogenous sulphur-containing amino acids, L-cysteine sulphinate, L-cysteate, L-homocysteine sulphinate and L-homocysteate, on the production of glutamate receptor antagonist, kynurenic acid (KYNA), was evaluated....
28.
Luchowski P, Luchowska E, Turski W, Urbanska E
Neurosci Lett . 2002 Sep; 330(1):49-52. PMID: 12213632
The aim of the present study was to evaluate the effect of mitochondrial inhibitors, 1-methyl-4-phenylpyridinium (MPP(+)) and 3-nitropropionic acid (3-NPA), on the brain production of endogenous glutamate antagonist, kynurenic acid...
29.
Stazka J, Luchowski P, Wielosz M, Kleinrok Z, Urbanska E
Eur J Pharmacol . 2002 Jul; 448(2-3):133-7. PMID: 12144932
Rat aortic slices produced and liberated the endogenous antagonist of glutamate receptors, kynurenic acid, upon exposure to L-kynurenine. Endothelium-denuded slices did not synthesize any measurable amount of kynurenic acid, indicating...
30.
Luchowska E, Luchowski P, Wielosz M, Kleinrok Z, Czuczwar S, Urbanska E
Pharmacol Biochem Behav . 2002 Jan; 71(1-2):223-31. PMID: 11812526
The anticonvulsive potential of classical antiepileptics co-administered with beta-adrenergic receptor antagonists against generalized tonic-clonic seizures was evaluated in the model of maximal electroshock (MES)-induced convulsions. Propranolol, acebutolol, metoprolol and atenolol...