Piotr Lacina
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Explore the profile of Piotr Lacina including associated specialties, affiliations and a list of published articles.
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24
Citations
213
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Recent Articles
1.
Dratwa-Kuzmin M, Lacina P, Wysoczanska B, Kilinska D, Siemaszko J, Sobczyk-Kruszelnicka M, et al.
J Cancer Res Clin Oncol
. 2025 Mar;
151(3):109.
PMID: 40082305
Introduction: Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase that maintains genome stability by maintaining telomere length (TL). The massive proliferation of donor cells in the recipient's body...
2.
Lacina P, Porzuczek D, Bogunia-Kubik K, Mazur G, Butrym A
Dent Med Probl
. 2024 Dec;
61(6):885-892.
PMID: 39704419
Background: Multiple myeloma (MM) is a hematological malignancy characterized by the presence of abnormal plasma cells. It is associated with anemia, bone lesions and renal dysfunction. Immunomodulatory drugs (IMiDs) are...
3.
Nihtila J, Penna L, Salmenniemi U, Itala-Remes M, Crossland R, Gallardo D, et al.
Sci Rep
. 2024 Nov;
14(1):26988.
PMID: 39506082
Natural killer (NK) cells recognize and may kill malignant cells via their cell surface receptors. Killer cell immunoglobulin-like receptor (KIR) genotypes of donors have been reported to adjust the risk...
4.
Siemaszko J, Lacina P, Szymczak D, Szeremet A, Majcherek M, Czyz A, et al.
Hum Immunol
. 2024 Sep;
85(6):111147.
PMID: 39332041
Despite new treatment strategies, graft-versus-host disease (GvHD) remains a formidable complication after allogeneic hematopoietic stem cell transplantation (HSCT). This study aimed to investigate the impact of polymorphisms and expression of...
5.
Nihtila J, Salmenniemi U, Itala-Remes M, Crossland R, Gallardo D, Bogunia-Kubik K, et al.
Hum Immunol
. 2024 Mar;
85(3):110791.
PMID: 38553383
Background: A genetic polymorphism, rs2204985, has been reported to be associated with the diversity of T-cell antigen receptor repertoire and TREC levels, reflecting the function of the thymus. As the...
6.
Siemaszko J, Lacina P, Szymczak D, Szeremet A, Majcherek M, Czyz A, et al.
Front Immunol
. 2023 Oct;
14:1227897.
PMID: 37901227
Transplantation of hematopoietic stem cells (HSCT) is a procedure commonly used in treatment of various haematological disorders which is associated with significantly improved survival rates. However, one of its drawbacks...
7.
Dratwa M, Lacina P, Butrym A, Porzuczek D, Mazur G, Bogunia-Kubik K
Sci Rep
. 2023 Sep;
13(1):15792.
PMID: 37737335
Telomere dysfunction is a notable event observed in many cancers contributing to their genomic instability. A major factor controlling telomere stability is the human telomerase reverse transcriptase catalytic subunit (hTERT)....
8.
Gail L, Schell K, Lacina P, Strobl J, Bolton S, Ulriksen E, et al.
Front Immunol
. 2023 Jul;
14:1199422.
PMID: 37435079
Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects many patients after allogeneic hematopoietic stem cell transplantation. Although we have made substantial progress in understanding disease pathogenesis and the...
9.
Lacina P, Crossland R, Wielinska J, Czyz A, Szeremet A, Ussowicz M, et al.
Adv Clin Exp Med
. 2022 Nov;
32(5):539-544.
PMID: 36398373
Background: Chronic graft-versus-host disease (cGvHD) is a complex disorder that typically manifests after allogeneic hematopoietic stem cell transplantation (HSCT). It is a major cause of non-relapse mortality, which makes finding...
10.
Wicherska-Pawlowska K, Bogunia-Kubik K, Kuszczak B, Lacina P, Dratwa M, Jazwiec B, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36076988
Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-I-like receptors (RLRs) are major elements of the innate immune system that recognize pathogen-associated molecular patterns. Single-nucleotide polymorphisms (SNPs) in the TLR, NLR,...